Human GM-CSF Phycoerythrin MAb (Clone 6804) (100 TESTS)【科瑞奥博】

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Human GM-CSF Phycoerythrin MAb (Clone 6804) (100 TESTS)

货号： IC615P 基本售价： 4243.4 元规格： 100 Tests

产品信息

概述
货号	IC615P
别名	colony stimulating factor 2 (granulocyte-macrophage); Colony-stimulating factor; CSF; CSF2; GM-CSF; GMCSFgranulocyte-macrophage colony-stimulating factor; granulocyte-macrophage colony stimulating factor; MGC131935; MGC138897; molgramostin; sargramostim
全称	Granulocyte Macrophage Growth Factor
反应种属	Human
应用	Intracellular Staining by Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects human GM-CSF in ELISAs. In ELISAs, this antibody does not cross-react with recombinant mouse (rm) GM‑CSF, rrGM‑CSF, rhM‑CSF, rhG‑CSF, rhIL‑5‑R alpha, or rhIL‑3 R alpha.
使用方法	Intracellular Staining by Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	1437 (Human); 12981 (Mouse); 116630 (Rat); 397208 (Porcine); 403923 (Canine); 493805 (Feline)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Human CD4(+) T cells recognize an epitope within alpha-fetoprotein sequence and develop into TGF-beta-producing CD4(+) T cells. Authors: Alisa A, Boswell S, Pathan AA, Ayaru L, Williams R, Behboudi S J. Immunol., 2008;180(7):5109-17. Species: Human Sample Type: Whole Cells Application: Flow High-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis. Authors: Uchida K, Nakata K, Trapnell BC, Terakawa T, Hamano E, Mikami A, Matsushita I, Seymour JF, Oh-Eda M, Ishige I, Eishi Y, Kitamura T, Yamada Y, Hanaoka K, Keicho N Blood, 2004;103(3):1089-98. Species: Human Sample Type: Whole Tissue Application: IHC Paraffin-embedded
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	E. coli-derived recombinant human GM-CSF Ala18-Glu144 Accession # P04141
生物活性	Human
标记	Phycoerythrin
背景	GM-CSF is a growth factor produced by a variety of lymphoid cells. It binds to receptor heterodimers consisting of a GM-CSF-specific alpha chain and the common beta chain that is shared by the high affinity receptors for IL-3 and IL-5.
运输条件	Blue Ice
存放说明	4℃
参考文献	Common beta Chain Receptor Family Cytokines and Receptors in Allergy and Asthma Cytokines and Receptors in Angiogenesis Dendritic Cell Development Gametes and Fertilization gamma delta T Cells ICC / IHC Images: GM-CSF Inflammatory Mediators Isolation, Culture, and Identification of Natural Killer Cells Macrophage Activation Markers Myeloid-derived Suppressor Cells (MDSC) Natural Killer T (NKT) Cells T Cell Cytokine Signaling

参考图片

Detection of GM‑CSF in Human Dendritic Cells by Flow Cytometry. Human dendritic cells treated with LPS, Recombinant Human TNF‑ alpha (Catalog # 210-TA), and Recombinant Human TGF‑ beta 1 (Catalog # 240-B) were stained with Mouse Anti-Human GM‑CSF PE‑conjugated Monoclonal Antibody (Catalog # IC615P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005). View our protocol for Staining Intracellular Molecules.