Human Integrin beta 6 Phycoerythrin MAb (Clone 437211) (100 TESTS)【科瑞奥博】

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Human Integrin beta 6 Phycoerythrin MAb (Clone 437211) (100 TESTS)

货号： FAB4155P 基本售价： 4243.4 元规格： 100 Tests

产品信息

概述
货号	FAB4155P
别名	integrin beta-6; integrin, beta 6; ITGB6
反应种属	Human
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects human Integrin beta 6 in direct ELISAs.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	3694 (Human); 16420 (Mouse); 29302 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Highly invasive melanoma cells activate the vascular endothelium via an MMP-2/integrin alphavbeta5-induced secretion of VEGF-A. Am. J. Pathol., 2012;181(2):693-705. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Chinese hamster ovary cell line CHO-derived recombinant human Integrin alpha V beta 6 Phe31-Val992 (Integrin alpha V) and Gly22-Asn707 (Integrin beta 6) Accession # P18564 (Integrin beta 6)
生物活性	Human
标记	Phycoerythrin
背景	Integrin beta 6 (ITG beta 6) is a 95 kDa member of the Integrin beta family. It forms noncovalent heterodimers with Integrin alpha V and appears on epithelia following injury or inflammation. It activates TGF-beta and assists keratinocyte migration. Human Integrin beta 6 is a type I transmembrane glycoprotein that is 767 amino acids (aa) in length. It contains a 688 aa extracellular domain (ECD) (aa 22-709) that incorporates a 241 aa VWF-A domain. Over aa 22-707, human integrin beta 6 ECD shares 90% and 93% aa sequence identity with mouse and pig integrin beta 6 ECD, respectively.
运输条件	Blue Ice
存放说明	4℃
参考文献	Actin Stress Fibers and Focal Adhesions During EMT Adhesion Molecules Epithelial Cell Polarity HGF/SF Activation of Integrins ICC / IHC Images: Integrin beta 6 Integrin Ligands at a Glance (J. Cell. Sci.) Integrin Subunit Interactions Integrins and Associated Molecules

参考图片

Detection of Integrin beta 6 in HT‑29 Human Cell Line by Flow Cytometry. HT‑29 human colon adenocarcinoma cell line was stained with Mouse Anti-Human Integrin beta 6 PE‑conjugated Monoclonal Antibody (Catalog # FAB4155P, filled histogram) or isotype control antibody (Catalog # IC0041P, open histogram). View our protocol for Staining Membrane-associated Proteins.