货号 | FAB2404C |
别名 | ADP-ribosyl cyclase 1; ADP-ribosyl Cyclase; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase; cADPr hydrolase 1; CD38 antigen (p45); CD38 antigen; CD38 molecule; CD38; Cyclic ADP-ribose hydrolase 1; Cyclic ADP-ribose Hydrolase; EC 3.2.2.5; NAD(+) nucleosidase; T10 | 全称 | Cluster of Differentiation 38 |
反应种属 | Human |
应用 | Flow Cytometry(10 µL/106cells) |
目标/特异性 | Detects human CD38 in flow cytometry. |
使用方法 | Flow Cytometry: 10 µL/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 952 (Human); 12494 (Mouse); 25668 (Rat) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | NS0 mouse myeloma cell line transfected with human CD38 Met1-Ile300 Accession # P28907 |
生物活性 | Human |
标记 | PerCP |
背景 | CD38, also known as ADP-ribosyl cyclase, is a Type II integral membrane protein. The enzyme is able to transform NAD(P)+ into three different products with calcium mobilizing ability, cyclic ADP-ribose, NAADP+, and ADP-ribose (1). CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells (2, 3). Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells (4, 5). |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Detection of CD38 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD38 PerCP‑conjugated Monoclonal Antibody (Catalog # FAB2404C, filled histogram) or isotype control antibody (Catalog # IC003C, open histogram). View our protocol for Staining Membrane-associated Proteins. | |
Detection of CD38 in Human PBMCs gated on CD19+CD3- cells by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) gated on CD19+CD3- cells were stained with Mouse Anti-Human CD38 PerCP‑conjugated Monoclonal Antibody (Catalog # FAB2404C) and Mouse Anti-Human MS4A1/CD20 APC‑conjugated Monoclonal Antibody (Catalog # FAB4225A). View our protocol for Staining Membrane-associated Proteins. |