货号 | FAB36551R-100 |
别名 | Cannabinoid R2; cannabinoid receptor 2 (macrophage); CannabinoidR2; CB-2; CB2cannabinoid receptor 2; CB2R; CNR2; CX5; CX5testis-dominant CNR2 isoform CB2; hCB2 | 全称 | Cannabinoid Receptor 2 |
应用 | Flow Cytometry |
目标/特异性 | Detects human Cannabinoid R2/CB2/CNR2 in direct ELISAs. Stains human Cannabinoid R2/CB2/CNR2 transfectants but not irrelevant transfectants in flow cytometry. |
使用方法 | Flow Cytometry: 5 µL/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 1269 (Human); 12802 (Mouse); 57302 (Rat) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | Human embryonic kidney cell line HEK293-derived transfected with human Cannabinoid R2/CB2/CNR2 Met1-Cys360 Accession # NP_001832 |
生物活性 | Human |
标记 | Alexa Fluor 647 |
背景 | Cannabinoid R2 (Cannabinoid Receptor 2), also called CB2 or CNR2, is a 7TM protein that belongs to the family of G protein-coupled receptors, class A. Cannabinoid R2 is expressed in the periphery, notably by hematopoietic cells, in contrast to Cannabinoid R1 which is expressed predominantly in the central nervous system and gut. Cannabinoid R2 on lymphocytes and macrophages binds cannabinoids and modulates cytokine secretion. With the exception of their divergent C‑terminal tails, human Cannabinoid R2 shares 82% amino acid sequence identity with mouse and rat Cannabinoid R2. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Detection of Cannabinoid R2/CB2/CNR2 in HEK293 Human Cell Line Transfected with Human Cannabinoid R2/CB2/CNR2 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with either (A) human Cannabinoid R2/CB2/CNR2 or (B) irrelevant transfectants and eGFP was stained with Mouse Anti-Human Cannabinoid R2/CB2/CNR2 Alexa Fluor® 647-conjugated Monoclonal Antibody (Catalog # FAB36551R). Quadrant markers were set based on control antibody staining (Catalog # IC0041R). View our protocol for Staining Membrane-associated Proteins. |