Human Integrin alpha V/CD51 Phycoerythrin MAb (Clone P2W7) (100 TESTS)【科瑞奥博】

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Human Integrin alpha V/CD51 Phycoerythrin MAb (Clone P2W7) (100 TESTS)

货号： FAB1219P 基本售价： 3955.9 元规格： 100 Tests

产品信息

概述
货号	FAB1219P
别名	antigen identified by monoclonal L230; CD51 antigen; CD51; integrin alpha-V; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); ITGAV; MSK8; Vitronectin Receptor alpha; Vitronectin receptor subunit alpha; VNRA; VNRADKFZp686A08142
反应种属	Human
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects the ectodomain of human Integrin alpha V/CD51.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	3685 (Human); 16410 (Mouse); 296456 (Rat)
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Ocular melanoma cell line
生物活性	Human
标记	Phycoerythrin
背景	Integrin alpha V (CD51; also vitronectin receptor subunit alpha) is a 140‑150 kDa member of the integrin alpha -chain family of adhesion molecules. It forms disulfide-linked integral membrane heterodimers with at least five beta -chains, including beta 1, 3, 5, 6 and 8. Human alpha V is a 1018 aa type I transmembrane glycoprotein that contains a 962 aa extracellular domain (ECD) (aa 31-992), and a short 32 aa cytoplasmic tail. The ECD contains seven FG (PheAlaGly)-GAP (GlyAlaPro) repeats that form a beta ‑propellor domain (aa 46-483). Furin cleavage of the alpha V ECD occurs after Gly889, generating a disulfide-linked heteromeric subunit alpha V chain. alpha V-containing integrins bind multiple ECM molecules, including vitronectin, osteopontin, MMP-2 and TSP. The ECD of human alpha V is 92% aa identical to mouse alpha V ECD.
运输条件	Blue Ice
存放说明	4℃
参考文献	Actin Stress Fibers and Focal Adhesions During EMT Adhesion Molecules Endothelial Cell Markers and Adhesion Molecules in Angiogenesis Epithelial Cell Polarity HGF/SF Activation of Integrins Human CD Marker Products ICC / IHC Images: Integrin alpha V/CD51 Integrin Ligands at a Glance (J. Cell. Sci.) Integrin Subunit Interactions Integrins and Associated Molecules Mesenchymal Stem Cell Markers Osteoblast and Osteoclast Markers VEGF Family

参考图片

Detection of Integrin alpha V/CD51 in HT1080 Human Cell Line by Flow Cytometry.

HT1080 human fibrosarcoma cell line was stained with Mouse Anti-Human Integrin alpha V/CD51 PE-conjugated Monoclonal Antibody (Catalog # FAB1219P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View our protocol for Staining Membrane-associated Proteins.