货号 | FAB11331G-100 |
别名 | AC133 Stargardt disease 4 (autosomal dominant); AC133; CD133 retinal 2; CD133; PROM1; prominin (mouse)-like 1; Prominin 1; PROML1 |
应用 | Flow Cytometry |
目标/特异性 | Detects human CD133. Stains human CD133 transfectants but not irrelevant transfectants in flow cytometry. |
使用方法 | Flow Cytometry: 5 µL/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 8842 (Human) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | NS0 mouse myeloma cell line transfected with human CD133 Accession # O43490 |
生物活性 | Human |
标记 | Alexa Fluor 488 |
背景 | CD133 antigen also known as prominin-1 is a glycoprotein that in humans is encoded by the PROM1 gene. It is a pentaspan transmembrane glycoprotein, with highly restricted expression on plasma membrane protrusions of epithelial and other cell types. CD133 is expressed in hematopoietic stem cells, endothelial progenitor cells, glioblastoma, neuronal and glial stem cells, as well as adult kidney, mammary glands, trachea, salivary glands, placenta, digestive tract, and testes. CD133 is used as a main marker for hematopoietic stem cells in transplant models. It has also been described as a marker of tumor initiating cells. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Detection of CD133 in NS0 Mouse Cell line Transfected with Human CD133 by Flow Cytometry. NS0 mouse myeloma cell line transfected with either human CD133 (filled histogram) or irrelevant transfectants (open histogram) was stained with Mouse Anti-Human CD133 Alexa Fluor® 488‑conjugated Monoclonal Antibody (Catalog # FAB11331G). View our protocol for Staining Membrane-associated Proteins. |