货号 | IC7157V-100UG |
别名 | DTX1/DTX4 | 全称 | Deltex 1/4 |
应用 | Intracellular Staining by Flow Cytometry |
目标/特异性 | Detects human DTX1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100%cross-reactivity with recombinant human DTX4 is observed. |
使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
免疫原 | E. coli-derived recombinant human DTX1/DTX4 Met1-Phe147 Accession # Q86Y01 |
生物活性 | Human |
标记 | Alexa Fluor 405 |
背景 | Deltex-1 (DTX1) is an approximately 75 kDa cytoplasmic and nuclear ubiquitin ligase that interacts with the Notch-1 intracellular domain and regulates Notch-induced gene transcription. It contains two WWE domains (aa 14-94 and aa 95-171) and one RING-type zinc finger (aa 411-472). Within aa 1-147, human Deltex-1 shares 97% aa sequence identity with mouse and rat Deltex-1. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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