| 货号 | IC6425V-100UG |
| 别名 | ACLP; ACLPadipocyte enhancer binding protein 1; AE binding protein 1; AE-binding protein 1adipocyte enhancer-binding protein 1; AEBP1; Aortic carboxypeptidase-like protein; FLJ33612 | 全称 | Aortic Carboxypeptidase-like Protein |
| 应用 | Intracellular Staining by Flow Cytometry |
| 目标/特异性 | Detects human ACLP in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse ACLP is observed. |
| 使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 165 (Human) |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human ACLP Glu345-Phe1158 Accession # Q8IUX7 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 405 |
| 背景 | Aortic carboxypeptidase-like protein (ACLP), also known as adipocyte enhancer binding protein (AEBP1), is a 175 kDa molecule that contains a discoidin-like domain (aa 383-540) and a peptidase-like domain (aa 560-942). It is expressed in proliferating adipocytes and represses the transcription of FABP4. ACLP promotes macrophage cholesterol retention, the formation of foam cells, and inflammatory responses. It is also an extracellular matrix-associated protein found in fibrotic tissues including vascular smooth muscle. An alternately spliced isoform lacks aa 1-457 and has an altered sequence at its N-terminus. Over aa 345-1158, human ACLP shares 88% aa sequence identity with mouse and rat ACLP. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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