货号 | IC5275N-100UG |
别名 | claudin 8; Claudin8; Claudin-8; CLDN8; human CLDN8 gene for claudin-810claudin-8 |
应用 | Intracellular Staining by Flow Cytometry |
目标/特异性 | Detects human Claudin‑8. Stains human Claudin-8 transfectants but not irrelevant transfectants. |
使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 9073 (Human); 54420 (Mouse); 304124 (Rat) |
免疫原 | HEK293 human embryonic kidney cell line transfected with human Claudin-8 Met1-Val225 (Ser151Pro) Accession # P56748 |
生物活性 | Human |
标记 | Alexa Fluor 700 |
背景 | Claudin-8 is a 225 amino acid (aa), 25 kDa four-transmembrane protein in the Claudin family of tight junction proteins. It is selectively expressed in tight junctions in the kidney thin descending limb, distal tubule and collecting duct, but is also found in liver and intestinal tight junctions. It is thought to function as an ion barrier protein. The extracellular portions of human Claudin-8 share 86% and 89% aa identity with corresponding portions of mouse and rat Claudin-8, respectively. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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