货号 | IC5048G-100UG |
别名 | CD63 antigen (melanoma 1 antigen); CD63 antigen; CD63 molecule; CD63; Granulophysin; Lamp-3; Lysosomal-associated membrane protein 3; ME491; melanoma 1 antigen; Melanoma-associated antigen ME491; melanoma-associated antigen MLA1; MLA1lysosome-associated membrane glycoprotein 3; Ocular melanoma-associated antigen; OMA81H; tetraspanin-30; Tspan30; tspan-30; TSPAN30granulophysin |
应用 | Intracellular Staining by Flow Cytometry |
目标/特异性 | Stains human CD63 transfectants but not irrelevant transfectants. |
使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 967 (Human); 12512 (Mouse); 29186 (Rat); 474391 (Canine) |
免疫原 | HEK293 human embryonic kidney cell line transfected with human CD63 Met1-Met238 Accession # P08962 |
生物活性 | Human |
标记 | Alexa Fluor 488 |
背景 | CD63, also known as LAMP-3 or ME491 (melanoma-associated antigen), is a 30-60 kDa member of the tetraspanin superfamily of protein trafficking proteins. CD63 is ubiquitously expressed and found in late endocytic vesicles, but following cell activation is also present on the plasma membrane. Interaction of CD63 with other membrane proteins or adaptors regulates cell activities such as adhesion, migration and degranulation. Extracellular regions of human CD63 share 67% and 65% amino acid sequence identity with mouse and rat CD63, respectively. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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