| 货号 | IC4866V-100UG |
| 别名 | AATK; AATYK; AATYKp35-binding protein; apoptosis-associated tyrosine kinaseCDK5-binding protein; Brain apoptosis-associated tyrosine kinase; EC 2.7.11; KIAA0641p35BP; Lemur tyrosine kinase 1; LMR1; LMR1EC 2.7.11.1; LMTK1; LMTK1AATYK1; p35BP; serine/threonine-protein kinase LMTK1 | 全称 | Apoptosis-associated Tyrosine Kinase |
| 应用 | Intracellular Staining by Flow Cytometry |
| 目标/特异性 | Detects human AATK in direct ELISAs. |
| 使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 9625 (Human); 11302 (Mouse); 690853 (Rat) |
| 免疫原 | E. coli-derived recombinant human AATK Asn421-Ala589 Accession # AAH47378 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 405 |
| 背景 | Apoptosis-associated tyrosine kinase (AATK) is a 155 kDa membrane-associated intracellular protein that promotes neurite extension and neuronal differentiation. Low extracellular potassium levels induce AATK phosphorylation and apoptosis in cerebellar granule cells. AATK negatively regulates the Na-K-2Cl cotransporter by promoting its PP1-dependent dephosphorylation. The two alternate splice forms of AATK also contain the sequences included in this immunogen. Within this region, human AATK shares 63% aa sequence identity with mouse AATK. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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