货号 | IC4676S-100UG |
别名 | GLUR2; glutamate metabotropic receptor 2; glutamate receptor, metabotropic 2; GPRC1B; GPRC1Bmetabotropic glutamate receptor 2; GRM2; mGlu2; mGluR2; MGLUR2glutamate receptor homolog; mGluR7 | 全称 | Metabotropic Glutamate Receptor 2 |
应用 | Intracellular Staining by Flow Cytometry |
目标/特异性 | Detects human mGluR2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross‑reactivity with the N-terminal regions of recombinant human mGluR1, -3, -4, -5, -7, or -8 is observed. |
使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 2912 (Human); 108068 (Mouse); 24415 (Rat) |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human mGluR2 Glu19-Ser498 Accession # Q14416 |
生物活性 | Human |
标记 | Alexa Fluor 750 |
背景 | Metabotropic glutamate receptor 2 (mGluR2) is an 872 aa, predicted 96 kDa multipass G protein coupled inhibitory receptor belonging to group II of the metabotropic glutamate receptor family. It is localized largely on the presynaptic side of glutamatergic and other neurotransmitter synapses in areas of the forebrain. mGluR2 activity is potentially involved in some anxiety disorders. The long N‑terminal extracellular region of human mGluR2 (aa 1‑498) shares 97% aa identity with either mouse or rat mGluR2. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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