| 货号 | FAB8398G-100UG |
| 别名 | AIT; AITSolute carrier family 5 member 8; Apical iodide transporter; Electrogenic sodium monocarboxylate cotransporter; MGC125354; SLC5A8; SMCT; SMCTSMCT1; Sodium iodide-related cotransporter; sodium-coupled monocarboxylate transporter 1; solute carrier family 5 (iodide transporter), member 8 | 全称 | Solute Carrier Family 5 Iodide Transporter), Member 8 |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects HEK293 human embryonic kidney cell line transfected with human SLC5A8/SMCT1 by Flow Cytometry. Does not detect untransfected or irrelevant transfected HEK293 cells. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 160728 (Human); 216225 (Mouse); 500820 (Rat) |
| 免疫原 | NS0 mouse myeloma cell line transfected with human SLC5A8/SMCT1 Met1-Leu610 Accession # NP_666018 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 488 |
| 背景 | SLC5A8/SMCT1 (Solute Carrier family 5, member 8) is a member of the solute carrier family of multi-pass membrane proteins. SLC5A8 has been shown to transport iodide by a passive mechanism. It also transports monocarboxylates and short-chain fatty acids by a sodium-coupled mechanism. SLC5A8 nuclear translocation and loss of expression are associated with poor outcome in pancreatic ductal adenocarcinoma (1). It may be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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