| 货号 | FAB6708G-100UG |
| 别名 | AREB6; AREB6MGC133261; BZP; delta-crystallin enhancer binding factor 1; DELTAEF1; FECD6; Negative regulator of IL2; NIL-2-A zinc finger protein; NIL2A; NIL-2-A; posterior polymorphous corneal dystrophy 3; PPCD3; TCF8; TCF-8; TCF8BZP; transcription factor 8 (represses interleukin 2 expression); Transcription factor 8; ZEB; ZEB1; ZFHEP; ZFHX1A; zinc finger E-box binding homeobox 1; zinc finger E-box-binding homeobox 1; zinc finger homeodomain enhancer-binding protein | 全称 | Zinc Finger E-box Binding Homeobox 1 |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects human ZEB1 in direct ELISAs. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 6935 (Human); 21417 (Mouse); 25705 (Rat) |
| 免疫原 | E. coli-derived recombinant human ZEB1 Glu430-Ser575 Accession # P37275 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 488 |
| 背景 | Zinc finger E-box-binding homeobox 1 (ZEB1; alsotranscription factor 8 (TCF-8)) is a 124 kDa member of the delta-EF1/ZFH-1C2H2-type zinc finger family. Human ZEB1is 1124 amino acids (aa) in length. The protein contains seven C2H2-type zincfingers and one homeobox DNA-binding domain. In addition, there are eight phosphoserines and onephosphothreonine. Residues 989-1124 makeup a glutamine-rich area. Within aa 430-575, human ZEB1shares 84% and 82% aa sequence identity with mouse and rat ZEB1, respectively. The protein is expressed in heart andskeletal muscle, and defects in ZEB1 are the cause of posterior polymorphouscorneal dystrophy type 3, a rare disease involving metaplasia and overgrowth ofthe corneal endothelial cells. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
|