| 货号 | FAB5764G-100UG |
| 别名 | 5-HT1C; 5-HT-1C; 5HT2C; 5-HT2C; 5-HT-2C; 5-HT2C5-hydroxytryptamine receptor 1C; 5-HTR2C; 5-hydroxytryptamine (serotonin) receptor 2C; 5-hydroxytryptamine receptor 2C; HTR1C; HTR2C; serotonin 5-HT-2C receptor; Serotonin Receptor 2C | 全称 | 5-Hydroxytryptamine Receptor 2C |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects human 5HT2C in direct ELISAs. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 3358 (Human); 15560 (Mouse); 25187 (Rat) |
| 免疫原 | NS0 mouse myeloma cell line transfected with human 5HT2C |
| 生物活性 | Human |
| 标记 | Alexa Fluor 488 |
| 背景 | 5HT2C is a 45 kDa 7TM receptor for serotonin and is neuronally expressed in the limbic system of the brain. The release of dopamine due to 5HT2C ligation regulates mood, appetite, and motivation. 5HT2C is an important pharmacologic target in the treatment of psychosis, schizophrenia, depression, anxiety, and migrane headaches. Multiple isoforms of 5HT2C can be generated by RNA editing. Human 5HT2C shares 89% aa sequence identity with mouse and rat 5HT2C. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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