| 货号 | FAB4279V-100UG |
| 别名 | Claudin10b; Claudin-10b; CLDN10; CPETRL3; OSP-L |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects human Claudin‑10b. Stains human Claudin‑10b transfectants but not irrelevant transfectants. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 9071 (Human); 58187 (Mouse); 290485 (Rat) |
| 免疫原 | NS0 mouse myeloma cell line transfected with human Claudin‑10 b Isoform Met1-Val228 Accession # P78369 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 405 |
| 背景 | Claudin-10 is a 228 amino acid multipass membrane protein in the Claudin family of epithelial tight junction proteins. Two splice forms of human Claudin-10 have been described with a divergent N-terminal extracellular loop. Claudin-10b (Swiss-Prot isoform 1) is relatively cation-permeant compared to Claudin-10a and is widely expressed, while Claudin‑10a is restricted to the kidney cortex. Claudin-10 is overexpressed in some carcinomas. Human Claudin‑10b shares 94% aa sequence identity with mouse and rat Claudin-10. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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