| 货号 | FAB180S-100UG |
| 别名 | C-C CKR-5; C-C motif chemokine receptor 5 A159A; CCCKR5; CC-CKR-5FLJ78003; CCR5; CCR-5; CD195 antigen; CD195; chemokine (C-C motif) receptor 5; chemokine receptor CCR5; chemr13; CKR5; CKR-5; HIV-1 fusion coreceptor; IDDM22CMKBR5C-C chemokine receptor type 5 |
| 应用 | Flow Cytometry |
| 目标/特异性 | Specifically stains human CCR5 transfectants but not the parental cell line as detected by flow cytometry. It has also been shown to react with a CCR5/CCR2 chimera (5222) containing the amino-terminal domain of CCR5. However, this antibody does not react with CCR5 present on unfixed stimulated human PBMCs by flow cytometry. For additional information regarding epitope specificity for this antibody and other R&D Systems anti-human CCR5 antibodies, see Lee, B. et al., 1999, J. Biol. Chem. 274:9617. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 1234 (Human); 12774 (Mouse); 117029 (Rat); 484789 (Canine); 493769 (Feline) |
| 免疫原 | NS0 mouse myeloma cell line transfected with human CCR5 Met1-Leu352 Accession # P51681 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 750 |
| 背景 | CCR5 is a G protein-linked seven transmembrane domain chemokine receptor. CCR5 serves as a receptor for several chemokines including MIP-1 alpha, MIP-1 beta, MCP-2, and RANTES. It also functions as a coreceptor for Macrophage Tropic HIV-1 infection. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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