| 货号 | IC4728G-100UG |
| 别名 | Neuromedin B R; neuromedin B receptor; Neuromedin BR; neuromedin-B receptor; Neuromedin-B-preferring bombesin receptor; NMBR; NMB-R | 全称 | Neuromedin B Receptor |
| 应用 | Intracellular Staining by Flow Cytometry |
| 目标/特异性 | Detects human Neuromedin B R/NMBR. Stains human Neuromedin B R/NMBR transfectants but not irrelevant transfectants. |
| 使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 4829 (Human); 18101 (Mouse); 25264 (Rat) |
| 免疫原 | NS0 mouse myeloma cell line transfected with human NMBR Met1-Met390 Accession # AAB27330 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 488 |
| 背景 | Neuromedin B Receptor (NMBR) is an 80 kDa, 390 amino acid (aa) G-protein coupled 7-transmembrane glycoprotein receptor for bombesin-like peptides, binding Neuromedin B with high affinity and GRP (gastrin releasing peptide) with lower affinity. Neuromedin B R expression in the olfactory and central thalamic regions of the brain plays a role in thermoregulation. It has also been shown to be mitogenic in colonic epithelium. Expression in the pituitary gland is important for regulation of the pituitary-thyroid axis. Within extracellular domains, human Neuromedin B R shares 86% and 82% aa identity with mouse and rat Neuromedin B R, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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