| 货号 | IC38571G-100UG |
| 别名 | ADAP; Adhesion and degranulation promoting adaptor protein; adhesion and degranulation-promoting adaptor protein; FYB; FYB-120/130SLAP-130FYN-binding protein (FYB-120/130); FYN binding protein; FYN-binding protein; FYN-T-binding protein; p120/p130; PRO0823; SLAP130; SLP-76-associated phosphoprotein | 全称 | FYN Binding Protein (FYB-120/130) |
| 应用 | Intracellular Staining by Flow Cytometry |
| 目标/特异性 | Detects human FYB/ADAP/SLAP130 in direct ELISAs. |
| 使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 2533 (Human); 23880 (Mouse); 499537 (Rat) |
| 免疫原 | E. coli-derived recombinant human FYB/ADAP/SLAP130 Ala2-Gly274 Accession # O15117 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 488 |
| 背景 | Human SH2 domain containing leukocyte protein-76-Associated Phosphoprotein of 130 kDa (SLAP130), also known as Fyb-120 and ADAP, is an 86 kDa, 783 amino acid, cytoplasmic protein that runs anomalously as a 120‑130 kDa protein in SDS-PAGE. Human SLAP130 is a hematopoietic-specific adaptor that associates with other cytoplasmic proteins such as SH2-containing Leukocyte Phosphoprotein of 76 kDa (SLP-76). Adaptors integrate signals from surface receptors and are essential components of many immune cell-signaling cascades. There is at least one known alternatively-spliced SLAP130 isoform which contains an additional 46 aa. Over the region used as immunogen, SLAP130 is 66% and 76% identical to the corresponding canine and mouse proteins, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |