| 货号 | IC29391S-100UG |
| 别名 | CA6; Carbonate dehydratase VI; carbonic anhydrase 6; Carbonic Anhydrase VI; carbonic anhydrase VIGUSTIN; CA-VI; EC 4.2.1.1; Gustin; MGC21256; Salivary carbonic anhydrase; Secreted carbonic anhydrase |
| 应用 | Intracellular Staining by Flow Cytometry |
| 目标/特异性 | Detects human Carbonic Anhydrase VI in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human Carbonic Anhydrase 1, 2, 3, 4, 5A, 5B, 7, 8, or 9 is observed. |
| 使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 765 (Human); 298657 (Rat) |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human Carbonic Anhydrase VI Gln18-Asn308 Accession # EAW71606 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 750 |
| 背景 | Carbonic Anhydrase catalyzes the reversible reaction of CO2 + H2O = HCO3- + H+, which is fundamental to many processes such as respiration, renal tubular acidification and bone resorption (1). Topics in a CA meeting (6th International Conference on the CAs, June 20‑25, 2003, Slovakia) ranged from the use of CAs as markers for tumor and hypoxia in the clinic, as a nutritional supplement in milk, and as a tool for CO2 removal and mosquito control in industry. Carbonic Anhydrase VI, also known as gustin and salivary Carbonic Anhydrase, is a zinc‑metalloprotein that constitutes about 3% of human parotid saliva protein (2, 3). It was decreased in patients with loss of taste and pathological changes in taste buds (4). It is also an elementary component of milk. It plays an important role in normal growth and development of the infant alimentary tract (5). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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