| 货号 | FAB8400U-100UG |
| 别名 | natural resistance-associated macrophage protein 1; LSH; member 1; NRAMP 1; NRAMP1; NRAMP1solute carrier family 11 (sodium/phosphate symporters), member 1; NRAMPnatural resistance-associated macrophage protein 1; SLC11A1; solute carrier family 11 (proton-coupled divalent metal ion transporters) | 全称 | Natural Resistance-associated Macrophage Protein 1 |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects HEK293 human embryonic kidney cell line transfected with human NRAMP1/SLC11A1 by Flow Cytometry. Does not detect untransfected or irrelevant transfected HEK293 cells. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 6556 (Human); 18173 (Mouse); 316519 (Rat) |
| 免疫原 | NS0 mouse myeloma cell line transfected with human NRAMP1/SLC11A1 Met1-Gly550 Accession # NP_000569 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 350 |
| 背景 | NRAMP1/SLC11A1 (Natural Resistance-Associated Macrophage Protein 1/Solute Carrier family 11, member 1) is a member of the solute carrier family of multi-pass membrane proteins. It functions as a proton-coupled divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in SLC11A1 have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn’s disease. Alternatively spliced variants that encode different protein isoforms have been described. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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