| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Negative regulation of osteoclast precursor differentiation by CD11b and beta2 integrin-B-cell lymphoma 6 signaling.
Authors: Park-Min K, Lee E, Moskowitz N, Lim E, Lee S, Lorenzo J, Huang C, Melnick A, Purdue P, Goldring S, Ivashkiv L
J Bone Miner Res, 2013;28(1):135-49.
Species: Human
Sample Type: whole cells
Application: Flow
Delay of migrating leukocytes by the basement membrane deposited by endothelial cells in long-term culture.
Authors: Burton VJ, Butler LM, McGettrick HM, Stone PC, Jeffery HC, Savage CO, Rainger GE, Nash GB
Exp. Cell Res., 2011;317(3):276-92.
Species: Human
Sample Type: Whole Cells
Application: Flow
A systematic methodology for proteome-wide identification of peptides inhibiting the proliferation and migration of endothelial cells.
Authors: Karagiannis ED, Popel AS
Proc. Natl. Acad. Sci. U.S.A., 2008;105(37):13775-80.
Species: Human
Sample Type: Whole Cells
Application: Neut |
| 背景 | The Integrin beta 1 subunit, also known as CD29, associates with at least ten different Integrin alpha subunits. It regulates not only its multiple ligands, but activates a signaling cascade in its expressing cells. CD29 is proposed to play a role in cell adhesion, apoptosis, and differentiation (1,2). Over amino acids (aa) 21-728, human and mouse share 92% aa sequence identity. |
