货号 | FAB2266A |
别名 | CD61 antigen; CD61; GP3A; GP3Aplatelet glycoprotein IIIa; GPIIIA; GPIIIaintegrin beta-3; INGRB3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITG B3; ITGB3; Platelet membrane glycoprotein IIIa |
反应种属 | Human |
应用 | Flow Cytometry |
目标/特异性 | Detects human Integrin beta 3/CD61 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human Integrin beta 1, beta 2, recombinant mouse Integrin beta 4, or beta 6 is observed. |
使用方法 | Flow Cytometry: 10 µL/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 3690 (Human); 16416 (Mouse); 29302 (Rat) |
应用文献 | |
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Negative regulation of osteoclast precursor differentiation by CD11b and beta2 integrin-B-cell lymphoma 6 signaling. | |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | Chinese hamster ovary cell line CHO-derived recombinant human Integrin beta 3/CD61 Gly27-Asp718 Accession # P05106 |
生物活性 | Human |
标记 | Allophycocyanin |
背景 | Integrin beta 3, also called CD61, associates with the Integrin alpha IIb or alpha Vsubunits to form heterodimeric receptors for collagens, fibronectin,vitronectin, fibrinogen, Von willebrand factor or thrombospondin. alpha IIb/ beta 3, also known as GPIIb IIIa (Glycoprotein IIb-IIIa), is expressedon platelets. alpha V/ beta 3, also known as vitronectin receptor, is expressedon endothelial cells, some B cells, platelets and monocytes. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Detection of Integrin beta 3/CD61 in Human Peripheral Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human Integrin beta 3/CD61 APC‑conjugated Monoclonal Antibody (Catalog # FAB2266A, filled histogram) or isotype control antibody (Catalog # IC003A, open histogram). View our protocol for Staining Membrane-associated Proteins. |