Human Integrin alpha L/CD11a Fluorescein MAb (Clone 345913) (100 TESTS)【科瑞奥博】

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Human Integrin alpha L/CD11a Fluorescein MAb (Clone 345913) (100 TESTS)

货号： FAB3595F 基本售价： 3529.5 元规格： 100 Tests

产品信息

概述
货号	FAB3595F
别名	CD11 antigen-like family member A; CD11a antigen; CD11a; CD11Aantigen CD11A (p180), lymphocyte function-associated antigen 1, alphapolypeptide; integrin alpha-L; integrin gene promoter; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen1; alpha polypeptide); ITGAL; Leukocyte adhesion glycoprotein LFA-1 alpha chain; Leukocyte function-associated molecule 1 alpha chain; LFA-1 alpha; LFA-1; LFA1A; LFA-1A; Ly-15; Ly-21; lymphocyte function-associated antigen 1
反应种属	Human
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects human Integrin alpha L/CD11a in Western blots.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	3683 (Human); 16408 (Mouse); 308995 (Rat)
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Chinese hamster ovary cell line CHO-derived recombinant human Integrin alpha L/CD11a Tyr26-Met1089 (Tyr660Ile) Accession # CAA68747
生物活性	Human
标记	Fluorescein
背景	Integrin subunit alpha L/CD11a is a 180 kDa type I TM glycoprotein that interacts only with Integrin beta 2/CD18 to form LFA-1, a leukocyte adhesion protein which binds endothelial cell ICAM-1 through -4. Human Integrin alpha L contains a 1064 aa extracellular domain (ECD), a 20 aa TM sequence and a 58 aa cytoplasmic domain. The ECD contains seven repeats that form a beta-propeller structure and one inserted vWA domain (I domain) containing a metal ion-dependent adhesion site (MIDAS). Human and mouse Integrin alpha L ECD share 74% aa identity. CD11a has two splice variants, one which contains a 53 aa insert after Gln954, and a second which shows a deletion of aa 110-192.
运输条件	Blue Ice
存放说明	4℃
参考文献	Adhesion Molecules Adhesive Interactions in Allergy and Asthma Basophils Common Macrophage Markers HGF/SF Activation of Integrins Human CD Marker Products Integrin Ligands at a Glance (J. Cell. Sci.) Integrin Subunit Interactions Integrins and Associated Molecules Myeloid-derived Suppressor Cells (MDSC) Regulatory T Cells (Tregs)

参考图片

Detection of Integrin alpha L/CD11a in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human Integrin alpha L/CD11a Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB3595F, filled histogram) or isotype control antibody (Catalog # IC002F, open histogram). View our protocol for Staining Membrane-associated Proteins.