Human IL-4 R alpha Fluorescein MAb (Clone 25463) (100 TESTS)【科瑞奥博】

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Human IL-4 R alpha Fluorescein MAb (Clone 25463) (100 TESTS)

货号： FAB230F-100 基本售价： 3529.5 元规格： 100 Tests

产品信息

概述
货号	FAB230F-100
别名	CD124 antigen; CD124; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL4R; IL-4RA; IL4RACD124; IL-4R-alpha; interleukin 4 receptor; interleukin-4 receptor alpha chain; interleukin-4 receptor subunit alpha
全称	Interleukin 4 Receptor alpha
反应种属	Human
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects human IL‑4 R alpha in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-9 R, recombinant mouse IL-4 R, rhIL-5 R alpha, rhIL-5 R beta, rhIL-13 R alpha 1, or rhIL-13 R alpha 2 is observed.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	3566 (Human); 16190 (Mouse)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Epigenetic modulation enhances the therapeutic effect of anti-IL-13R alpha2 antibody in human mesothelioma xenografts. Clin. Cancer Res., 2012;17(9):2819-29. Species: Human Sample Type: Whole Cells Application: Flow An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice. Authors: Sindrilaru A, Peters T, Wieschalka S, Baican C, Baican A, Peter H, Hainzl A, Schatz S, Qi Y, Schlecht A, Weiss JM, Wlaschek M, Sunderkotter C, Scharffetter-Kochanek K J. Clin. Invest., 2011;121(3):985-97. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from ascites
免疫原	S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL‑4 R Gly24-His232 Accession # P24394
生物活性	Human
标记	Fluorescein
背景	Interleukin 4 receptor (IL-4 R) is the transmembrane ligand binding subunit of the heterodimeric IL-4 receptor complex. In the type I receptor complex, IL-4 R associates with the common gamma chain, whereas in the type II receptor complex, it associates with IL-13 R alpha 1. IL-4 R is expressed by B cells, T cells, monocytes and macrophages.
运输条件	Blue Ice
存放说明	4℃
参考文献	B Cell Activation B Cell Markers Common gamma Chain Receptor Family Cytokines and Receptors in Allergy and Asthma Cytokines and Receptors in Angiogenesis Cytokines and Receptors in Tfh Cell Differentiation and Function Human CD Marker Products ICC / IHC Images: IL-4 R alpha Interactive Pathway: IL-4 Signaling and its Primary Biological Effects in Different Immune Cell Types Interactive Pathway: IL-4 Signaling Pathways Macrophage Activation Markers Myeloid-derived Suppressor Cells (MDSC) Receptors in the Jak/STAT Pathway Regulatory T Cells (Tregs) T Cell Cytokine Signaling Th17 Cells Th2 Cells Th9 Cells

参考图片

Detection of IL‑4 R alpha in Daudi Human Cell Line by Flow Cytometry. Daudi human Burkitts lymphoma cell line was stained with Mouse Anti-Human IL‑4 R alpha Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB230F, filled histogram) or isotype control antibody (Catalog # IC003F, open histogram). View our protocol for Staining Membrane-associated Proteins.