货号 | FAB2266P |
别名 | CD61 antigen; CD61; GP3A; GP3Aplatelet glycoprotein IIIa; GPIIIA; GPIIIaintegrin beta-3; INGRB3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITG B3; ITGB3; Platelet membrane glycoprotein IIIa |
反应种属 | Human |
应用 | Flow Cytometry |
目标/特异性 | Detects human Integrin beta 3/CD61 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human Integrin beta 1, beta 2, recombinant mouse Integrin beta 4, or beta 6 is observed. |
使用方法 | Flow Cytometry: 10 µL/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 3690 (Human); 16416 (Mouse); 29302 (Rat) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | Chinese hamster ovary cell line CHO-derived recombinant human Integrin beta 3/CD61 Gly27-Asp718 Accession # P05106 |
生物活性 | Human |
标记 | Phycoerythrin |
背景 | Integrin beta 3, also called CD61, associates with the Integrin alpha IIb or alpha V subunits to form heterodimeric receptors for Collagens, Fibronectin, Vitronectin, Fibrinogen, Von Willebrand factor or Thrombospondin. alpha IIb/ beta 3, also known as GPIIb IIIa (Glycoprotein IIb-IIIa), is expressed on platelets. alpha V/ beta 3, also known as Vitronectin Receptor, is expressed on endothelial cells, some B cells, platelets and monocytes. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Detection of Integrin beta 3/CD61 in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human Integrin beta 3/CD61 PE‑conjugated Monoclonal Antibody (Catalog # FAB2266P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for Staining Membrane-associated Proteins. |