Human CD94 Phycoerythrin MAb (Clone 131412) (100 TESTS)
货号：
FAB1058P 基本售价：
3529.5 元 规格：
100 Tests
产品信息
概述| 货号 | FAB1058P |
| 别名 | CD94 antigen; CD94; CD94natural killer cells antigen CD94; Killer cell lectin-like receptor subfamily D member 1; killer cell lectin-like receptor subfamily D, member 1; KLRD1; KP43; NK cell receptor |
| 反应种属 | Human |
| 应用 | Flow Cytometry |
| 目标/特异性 | Recognizes human CD94 both in its homodimeric form and as a heterodimer with either NKG2A or NKG2C. |
| 使用方法 | Flow Cytometry: 10 µL/106cells
|
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 3824 (Human) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | BaF3 mouse pro-B cell line transfected with human CD94 and NKG2A |
| 生物活性 | Human |
| 标记 | Phycoerythrin |
| 背景 | CD94, also known as KLAD1, is a 30 kDa type II transmembrane protein with an extracellular C-type lectin domain. It is expressed by natural killer (NK) cells and a subset of CD8+ T cells, with cellular activation resulting in increased cell surface expression. Although CD94 can occur as a non-signaling homodimer, functional activity occurs when CD94 exists as a heterodimer with an NKG2 family member. A CD94/NKG2A heterodimer delivers an inhibitory signal to the expressing cell, whereas, a CD94/NKG2C heterodimer associates with the DAP12 adapter protein and delivers an activating signal. Both heterodimeric complexes recognize HLA-E with an associated peptide derived from the signal peptide of other HLA proteins. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - C-type Lectin Family
- Group 1 ILCs
- Human CD Marker Products
- Leukocyte Receptors/Markers in Allergy and Asthma
- Natural Killer T (NKT) Cells
- NKG2 Family Receptors
|
参考图片Detection of CD94 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD94 PE‑conjugated Monoclonal Antibody (Catalog # FAB1058P) and Mouse Anti-Human NCAM‑1/CD56 APC‑conjugated Monoclonal Antibody (Catalog # FAB2408A). Quadrant markers were set based on control antibody staining (Catalog # IC002P). View our protocol for Staining Membrane-associated Proteins. |
