| 货号 | FAB1748F |
| 简介 | Clone 216110 was used by HLDA to establish CD designation |
| 别名 | CD367; CLEC4A; CLECSF6; CLECSF6C-type lectin superfamily member 6; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 6; C-type lectin domain family 4 member A; C-type lectin domain family 4, member A; DCIRLLIR; DDB27; DDB27C-type lectin DDB27; Dendritic cell immunoreceptor; Lectin-like immunoreceptor; LLIR | 全称 | Dendritic Cell Immunoreceptor |
| 反应种属 | Human |
| 应用 | Flow Cytometry(10 µL/106cells) |
| 目标/特异性 | Detects human DCIR/CLEC4A in direct ELISAs and Western blots. |
| 使用方法 | Flow Cytometry: 10 µL/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 50856 (Human); 26888 (Mouse) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human DCIR isoform 1 Gln70-Leu237 Accession # Q9UMR7 |
| 生物活性 | Human |
| 标记 | Fluorescein |
| 背景 | DCIR, also known as Lectin-like Immunoreceptor (LLIR), is a type II transmembrane protein belonging to the C-type lectin domain family, and is designated CLEC4A (previously designated CLECSF6). Four transcript variants encoding distinct isoforms have been identified. DCIR contains one carbohydrate recognition domain in its C-terminal extracellular domain and an Immunoreceptor Tyrosine-based Inhibitory Motif (ITIM) in its cytoplasmic domain. Besides its association with dendritic cells, DCIR is expressed on B cells, monocytes/macrophages and granulocytes. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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Detection of DCIR/CLEC4A in Human Blood Neutrophils by Flow Cytometry. Human peripheral blood neutrophils were stained with Mouse Anti-Human DCIR/CLEC4A Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB1748F, filled histogram) or isotype control antibody (Catalog # IC002F, open histogram). View our protocol for Staining Membrane-associated Proteins. |
