Human CD11b/Integrin alpha M Allophycocyanin MAb (Cl ICRF44) (100 TESTS)
货号：
FAB1699A-100 基本售价：
3390.7 元 规格：
100 Tests
产品信息
概述| 货号 | FAB1699A-100 |
| 别名 | antigen CD11b (p170); CD11 antigen-like family member B; CD11b antigen; CD11b; CD11Bintegrin, alpha M (complement component receptor 3, alpha; also known as CD11b(p170), macrophage antigen alpha polypeptide); Cell surface glycoprotein MAC-1 subunit alpha; CR-3 alpha chain; CR3AMGC117044; Integrin alpha M; integrin alpha-M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; MAC-1; MAC1A; macrophage antigen alpha polypeptide; MO1A; neutrophil adherence receptor alpha-M subunit; Neutrophil adherence receptor; SLEB6 |
| 反应种属 | Human |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects human Integrin alpha M/CD11b. |
| 使用方法 | Flow Cytometry: 10 µL/106cells
|
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 3684 (Human); 16409 (Mouse) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | Mouse B cells |
| 生物活性 | Human |
| 标记 | Allophycocyanin |
| 背景 | The Integrin family proteins are heterodimeric transmembrane receptors composed of an alpha and a beta subunit. The Integrin alpha M subunit, also known as MAC-1 alpha subunit or CD11b, combines with the Integrin beta 2 subunit (CD18) to form the non-covalent heterodimer Integrin alpha M/ beta 2, also known as MAC-1 and complement receptor type 3 (CR3). Integrin alpha M/ beta 2 is expressed on granulocytes, macrophages, dendritic cells and natural killer cells. Upon activation, alpha M/ beta 2 can bind several ligands (including ICAM-1, fibrinogen and the C3 complement fragment C3bi) to mediate phagocyte adhesion, migration and ingestion of complement-opsonized particles. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Acute Lymphoblastic Leukemia
- Acute Myeloid Leukemia
- Adhesion Molecules
- Adhesive Interactions in Allergy and Asthma
- B Cell Chemotaxis, Migration, and Adhesion
- B Cell Markers
- Basophils
- Common Macrophage Markers
- Conventional/Classical Dendritic Cells
- Granulocyte Markers
- HGF/SF Activation of Integrins
- Human CD Marker Products
- ICC / IHC Images: CD11b/Integrin alpha M
- Inflammatory/Monocyte-derived Dendritic Cells
- Integrin Ligands at a Glance (J. Cell. Sci.)
- Integrin Subunit Interactions
- Integrins and Associated Molecules
- Isolation, Culture, and Identification of Natural Killer Cells
- Langerhans and Dermal Dendritic Cells
- Monocyte Markers
- Mouse Tissue-Resident Macrophage Markers
- Myeloid Lineage Markers
- Myeloid-derived Suppressor Cells (MDSC)
- Neuroinflammation
- Neutrophils
- Plasmacytoid Dendritic Cells
- T Cell Migration/Adhesion
|
参考图片Detection of Integrin alpha M/CD11b in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human Integrin alpha M/CD11b APC‑conjugated Monoclonal Antibody (Catalog # FAB1699A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins. |
