| 货号 | FAB1699V-100UG |
| 别名 | antigen CD11b (p170); CD11 antigen-like family member B; CD11b antigen; CD11b; CD11Bintegrin, alpha M (complement component receptor 3, alpha; also known as CD11b(p170), macrophage antigen alpha polypeptide); Cell surface glycoprotein MAC-1 subunit alpha; CR-3 alpha chain; CR3AMGC117044; Integrin alpha M; integrin alpha-M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; MAC-1; MAC1A; macrophage antigen alpha polypeptide; MO1A; neutrophil adherence receptor alpha-M subunit; Neutrophil adherence receptor; SLEB6 |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects human CD11b/Integrin alpha M. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 3684 (Human); 16409 (Mouse) |
| 免疫原 | Human rheumatoid synovial cells and monocytes |
| 生物活性 | Human |
| 标记 | Alexa Fluor 405 |
| 背景 | The Integrin family proteins are heterodimeric transmembrane receptorscomposed of an alpha and a beta subunit. The Integrin alpha M subunit, also knownas MAC-1 alpha subunit or CD11b, combines with the Integrin beta 2 subunit(CD18) to form the non-covalent heterodimer Integrin alpha M/ beta 2, also knownas MAC-1 and complement receptor type 3 (CR3). Integrin alpha M/ beta 2 isexpressed on granulocytes, macrophages, dendritic cells and naturalkiller cells. Upon activation, alpha M/ beta 2 can bind several ligands(including ICAM-1 fibrinogen and the C3 complement fragment C3bi) tomediate phagocyte adhesion, migration and ingestion ofcomplement-opsonized particles. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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