| 货号 | FAB5756F |
| 别名 | B10; CD203c antigen; CD203c; dJ1005H11.3 (phosphodiesterase I/nucleotide pyrophosphatase 3); dJ914N13.3 (phosphodiesterase I/nucleotide pyrophosphatase 3); ectonucleotide pyrophosphatase/phosphodiesterase 3; ectonucleotide pyrophosphatase/phosphodiesterase family member 3; E-NPP 3; gp130RB13-6; NPP3; PD-IBETA; PDNP3; PDNP3B10; Phosphodiesterase I beta; Phosphodiesterase I/nucleotide pyrophosphatase 3; phosphodiesterase-I beta | 全称 | Ectonucleotide Pyrophosphatase/Phosphodiesterase 3 |
| 反应种属 | Human |
| 应用 | Flow Cytometry(10 µL/106cells) |
| 目标/特异性 | Detects human ENPP‑3/CD203c. |
| 使用方法 | Flow Cytometry: 10 µL/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 5169 (Human) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | HEK293 human embryonic kidney cell line transfected with human ENPP‑3/CD203c Accession # O14638 |
| 生物活性 | Human |
| 标记 | Fluorescein |
| 背景 | CD203c is a 120-130 kDa type II transmembrane glycoprotein that belongs to the ectonucleotidase family, AP superfamily of enzymes. CD203c is also known as ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP-3) and it modulates purinergic signaling by hydrolysis of nucleotide di- and tri-phosphates plus sphingosylphosphorylenosine. Although CD203c is considered to be a marker for activated basophils and mast cells, it is also found constitutively or inducibly on bile duct epithelium, hepatocytes, duodenal columnar epithelium, osteoblasts, plasmacytoid dendritic cells, airway pseudostratified ciliated columnar epithelium and renal proximal tubule S3 segment cells. Within the ECD, human CD203c shares 81% aa sequence identity with mouse and rat CD203. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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Detection of ENPP‑3/CD203c in Human Whole Blood Lymphocytes and Monocytes by Flow Cytometry. Human whole blood lymphocytes and monocytes were stained with Mouse Anti-Human IL‑3 R alpha /CD123 PE‑conjugated Monoclonal Antibody (Catalog # FAB301P) and either (A) Mouse Anti-Human ENPP‑3/CD203c Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB5756F) or (B) Mouse IgG1 Fluorescein Isotype Control (Catalog # IC002F). View our protocol for Staining Membrane-associated Proteins. |
