| 货号 | FAB8450A-025 |
| 别名 | CHMD; FLOT1; folate transporter 1; FOLT; FOLThuman reduced folate carrier (RFC)10Intestinal folate carrier 1; IFC1; IFC-1; Placental folate transporter; Reduced folate carrier protein; REFC; RFC; RFC1; solute carrier family 19 (folate transporter), member 1; Solute carrier family 19 member 1 | 全称 | Solute Carrier Family 12 (Folate Transporter) Member 3 |
| 反应种属 | Human |
| 应用 | Flow Cytometry |
| 目标/特异性 | Stains human Reduced Folate Carrier/SLC19A1 transfectants but not irrelevant transfectants in flow cytometry. |
| 使用方法 | Flow Cytometry: 10 µL/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 6573 (Human); 20509 (Mouse); 29723 (Rat) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | NS0 mouse myeloma cell line transfected with human Reduced Folate Carrier/SLC19A1 Met1-Gln591 Accession # P41440 |
| 生物活性 | Human |
| 标记 | Allophycocyanin |
| 背景 | SLC19A1, also known as Reduced Folate Carrier protein, is a multi-pass transmembrane transporter that is involved in the regulation of intracellular concentrations of folate. There is an association between idiopathic Recurrent Spontaneous Abortion (RSA) and SLC19A1 polymorphisms that may be useful biomarkers for RSA risk. Three transcript variants encoding different isoforms have been found for this gene. Human and mouse SLC19A1 share only 58% amino acid (aa) sequence identity, with considerable divergence over the C-terminal 100 aa. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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Detection of Reduced Folate Carrier/SLC19A1 in HEK293 Human Cell Line Transfected with Human SLC19A1 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with human SLC19A1 and eGFP were stained with either (A) Mouse Anti-Human Reduced Folate Carrier/SLC19A1 APC‑conjugated Monoclonal Antibody (Catalog # FAB8450A) or (B) Mouse IgG2A Allophycocyanin Isotype Control (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins. |
