Human CD3 epsilon Fluorescein MAb (Clone UCHT1) (25 TESTS)【科瑞奥博】

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Human CD3 epsilon Fluorescein MAb (Clone UCHT1) (25 TESTS)

货号： FAB100F-025 基本售价： 1407.8 元规格： 25 Tests

产品信息

概述
货号	FAB100F-025
简介	Clone UCHT1 was used by HLDA to establish CD designation
别名	CD3e antigen; CD3e antigen, epsilon polypeptide (TiT3 complex); CD3e molecule, epsilon (CD3-TCR complex); CD3e; CD3-epsilon; FLJ18683; T3E; T-cell antigen receptor complex, epsilon subunit of T3; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; TCRE
反应种属	Human
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Recognizes the epsilon -chain of the CD3/T cell antigen receptor complex (McMichael, A.J. et al. (1987) Leucocyte Typing III: White Cell Differentiation Antigens, Oxford University Press, New York; Knapp, W. et al. (1989) Leucocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York; Schlossman, S. et al. (1995) Leucocyte Typing V: White Cell Differentiation Antigens, Oxford University Press, New York).
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	916 (Human); 12503 (Mouse)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. HIV-1 infection is characterized by profound depletion of CD161+ Th17 cells and gradual decline in regulatory T cells. Authors: Prendergast A, Prado JG, Kang YH, Chen F, Riddell LA, Luzzi G, Goulder P, Klenerman P AIDS, 2010;24(4):491-502. Species: Human Sample Type: Whole Cells Application: Flow Over-expression of receptor activator of nuclear factor-kappaB ligand (RANKL), inflammatory cytokines, and chemokines in periprosthetic osteolysis of loosened total hip arthroplasty. Authors: Wang CT, Lin YT, Chiang BL, Lee SS, Hou SM Biomaterials, 2010;31(1):77-82. Species: Human Sample Type: Whole Cells Application: Flow Natural killer lysis receptor (NKLR)/NKLR-ligand matching as a novel approach for enhancing anti-tumor activity of allogeneic NK cells. Authors: Markel G, Seidman R, Besser MJ PLoS ONE, 2009;4(5):e5597. Species: Human Sample Type: Whole Cells Application: Flow Cancer immunoediting by GITR (glucocorticoid-induced TNF-related protein) ligand in humans: NK cell/tumor cell interactions. Authors: Baltz KM, Krusch M, Bringmann A, Brossart P, Mayer F, Kloss M, Baessler T, Kumbier I, Peterfi A, Kupka S, Kroeber S, Menzel D, Radsak MP, Rammensee HG, Salih HR FASEB J., 2007;21(10):2442-54. Species: Human Sample Type: Whole Cells Application: Flow Substance P regulates macrophage inflammatory protein 3alpha/chemokine C-C ligand 20 (CCL20) with heme oxygenase-1 in human periodontal ligament cells. Authors: Lee SK, Pi SH, Kim SH, Min KS, Lee HJ, Chang HS, Kang KH, Kim HR, Shin HI, Lee SK, Kim EC Clin. Exp. Immunol., 2007;150(3):567-75. Species: Human Sample Type: Whole Cells Application: Functional Assay Herpes simplex virus-1 up-regulates IL-15 gene expression in monocytic cells through the activation of protein tyrosine kinase and PKC zeta/lambda signaling pathways. Authors: Ahmad R, Ennaciri J, Cordeiro P, El Bassam S, Menezes J J. Mol. Biol., 2006;367(1):25-35. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Human thymocytes (1)
生物活性	Human
标记	Fluorescein
背景	CD3 epsilon is one of at least four invariant proteins that associate with the variable antigen recognition chains of the T cell receptor and function in signal transduction.
运输条件	Blue Ice
存放说明	4℃
参考文献	Beverly, P.C.L. and R.E. Callard (1981) Eur. J. Immunol. 11:329.

参考图片

Detection of CD3 epsilon in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD19 APC‑conjugated Monoclonal Antibody (Catalog # FAB4867A) and either Mouse Anti-Human CD3 epsilon Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB100F) or (Catalog # IC002F). View our protocol for Staining Membrane-associated Proteins.