Human CD31/PECAM-1 Fluorescein MAb (Clone 9G11) (25 TESTS)【科瑞奥博】

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Human CD31/PECAM-1 Fluorescein MAb (Clone 9G11) (25 TESTS)

货号： FAB3567F-025 基本售价： 1407.8 元规格： 25 Tests

产品信息

概述
货号	FAB3567F-025
别名	adhesion molecule; CD31 antigen; CD31; CD31/EndoCAM; endoCAM; FLJ34100; FLJ58394; GPIIA; PECA1; PECAM1; PECAM-1; PECAM-1, CD31/EndoCAM; platelet endothelial cell adhesion molecule; platelet/endothelial cell adhesion molecule
全称	Platelet Endothelial Cell Adhesion Molecule 1
反应种属	Human
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects human CD31/PECAM‑1 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) E‑Selectin, rhICAM-1, -2, -3, rhVCAM-1, or recombinant mouse VCAM-1 is observed.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	5175 (Human); 18613 (Mouse); 29583 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Limited gene expression variation in human embryonic stem cell and induced pluripotent stem cell-derived endothelial cells. Authors: White M, Rufaihah A, Liu L, Ghebremariam Y, Ivey K, Cooke J, Srivastava D Stem Cells, 2013;31(1):92-103. Species: Human Sample Type: whole cells Application: Flow Dehydroepiandrosterone inhibits the TNF-alpha-induced inflammatory response in human umbilical vein endothelial cells. Authors: Gutierrez G, Mendoza C, Zapata E, Montiel A, Reyes E, Montano LF, Lopez-Marure R Atherosclerosis, 2007;190(1):90-9. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Activated HUVEC human umbilical vein endothelial cells
生物活性	Human
标记	Fluorescein
背景	The CD31 adhesion molecule, also known as PECAM-1, is expressed in large amounts on endothelial cells at intercellular junctions and on T cell subsets, and to a lesser extent on platelets and most other leukocytes such as monocytes and neutrophils. CD31 binds to itself homotypically, and also to the leukocyte integrin alpha v beta 3 heterotypically. CD31 is required for the transendothelial migration of leukocytes through intercellular junctions of vascular endothelial cells. CD31 has been found in human plasma, and the presence of this circulating isoform is suggested to modulate the transendothelial migration of leukocytes.
运输条件	Blue Ice
存放说明	4℃
参考文献	Cancer Biomarkers Endothelial Cell Differentiation Markers Endothelial Cell Markers Endothelial Cell Markers and Adhesion Molecules in Angiogenesis Endothelial Progenitor and Endothelial Cell Markers Endothelial Progenitor Cell Markers Hemangioblasts Human CD Marker Products ICC / IHC Images: CD31/PECAM-1 Immunoglobulin Superfamily CAMs ITIM/ITAM Immunoreceptors and Related Molecules Mini-review: Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1/CD31) Myeloid-derived Suppressor Cells (MDSC) Platelets T Cell Migration/Adhesion

参考图片

Detection of CD31/PECAM‑1 in Human Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human CD31/PECAM‑1 Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB3567F, filled histogram) or isotype control antibody (Catalog # IC002F, open histogram). View our protocol for Staining Membrane-associated Proteins.