Human CCR6 Fluorescein MAb (Clone 53103) (25 TESTS)【科瑞奥博】

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Human CCR6 Fluorescein MAb (Clone 53103) (25 TESTS)

货号： FAB195F-025 基本售价： 1407.8 元规格： 25 Tests

产品信息

概述
货号	FAB195F-025
简介	Clone 53103 was used by HLDA to establish CD designation
别名	BN-1; CC-CKR-6; CCR6; CCR-6; CD196 antigen; CD196; chemokine (C-C motif) receptor 6; CKR-L3G-protein coupled receptor 29; CKRL3LARC receptor; CMKBR6STRL22; DRY6; GPR29; GPR29C-C CKR-6; GPR-CY4; GPRCY4DRY-6; lymphocyte, 22; STRL22
反应种属	Human
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects human CCR6. Stains human CCR6 transfectants but not the parental cell line in flow cytometry. Does not cross-react with transfectants expressing human CCR1, CCR2, CCR3, CCR4, CCR5, CCR7, CXCR1, CXCR2, CXCR3, CXCR4, or STRL33.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	1235 (Human); 12458 (Mouse); 308163 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. IL-11 Induces Th17 Cell Responses in Patients with Early Relapsing-Remitting Multiple Sclerosis. Authors: Zhang X, Tao Y, Chopra M, Dujmovic-Basuroski I, Jin J, Tang Y, Drulovic J, Markovic-Plese S J Immunol, 2015;194(11):5139-49. Species: Human Sample Type: Whole Cells Application: Flow CCR2+CCR5+ T Cells Produce Matrix Metalloproteinase-9 and Osteopontin in the Pathogenesis of Multiple Sclerosis. Authors: Sato W, Tomita A, Ichikawa D, Lin Y, Kishida H, Miyake S, Ogawa M, Okamoto T, Murata M, Kuroiwa Y, Aranami T, Yamamura T J Immunol, 2012;189(10):5057-65. Species: Human Sample Type: Whole Cells Application: Flow Identification of human NK17/NK1 cells. Authors: Pandya AD, Al-Jaderi Z, Hoglund RA, Holmoy T, Harbo HF, Norgauer J, Maghazachi AA PLoS ONE, 2011;6(10):e26780. Species: Human Sample Type: Whole Cells Application: Flow Characterization of circulating dendritic cells in melanoma: role of CCR6 in plasmacytoid dendritic cell recruitment to the tumor. Authors: Charles J, Di Domizio J, Salameire D, Bendriss-Vermare N, Aspord C, Muhammad R, Lefebvre C, Plumas J, Leccia MT, Chaperot L J. Invest. Dermatol., 2010;130(6):1646-56. Species: Human Sample Type: Whole Tissue Application: IF Human beta-defensin 2 and 3 and their mouse orthologs induce chemotaxis through interaction with CCR2. Authors: Rohrl J, Yang D, Oppenheim JJ, Hehlgans T J. Immunol., 2010;184(12):6688-94. Species: Human Sample Type: Whole Cells Application: Flow HIV-1 infection is characterized by profound depletion of CD161+ Th17 cells and gradual decline in regulatory T cells. Authors: Prendergast A, Prado JG, Kang YH, Chen F, Riddell LA, Luzzi G, Goulder P, Klenerman P AIDS, 2010;24(4):491-502. Species: Human Sample Type: Whole Cells Application: Flow Lung myeloid dendritic cells coordinately induce TH1 and TH17 responses in human emphysema. Authors: Shan M, Cheng HF, Song LZ Sci Transl Med, 2009;1(4):4ra10. Species: Human Sample Type: Whole Cells Application: Flow Expression and role of CCR6/CCL20 chemokine axis in pulmonary sarcoidosis. Authors: Facco M, Baesso I, Miorin M, Bortoli M, Cabrelle A, Boscaro E, Gurrieri C, Trentin L, Zambello R, Calabrese F, Cassatella MA, Semenzato G, Agostini C J. Leukoc. Biol., 2007;82(4):946-55. Species: Human Sample Type: Whole Cells Application: Flow CC chemokine receptor 5 and CXC chemokine receptor 6 expression by lung CD8+ cells correlates with chronic obstructive pulmonary disease severity. Authors: Freeman CM, Curtis JL, Chensue SW Am. J. Pathol., 2007;171(3):767-76. Species: Human Sample Type: Whole Cells Application: Flow CCR6 colocalizes with CD18 and enhances adhesion to activated endothelial cells in CCR6-transduced Jurkat T cells. Authors: Maki W, Morales RE, Carroll VA, Telford WG, Knibbs RN, Stoolman LM, Hwang ST J. Immunol., 2002;169(5):2346-53. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from ascites
免疫原	NS0 mouse myeloma cell line transfected with human CCR6 Met1-Met374 Accession # P51684
生物活性	Human
标记	Fluorescein
背景	CCR6 is a seven transmembrane-spanning G protein-coupled receptor that binds the chemokine MIP-3 alpha and mediates the chemoattraction of B and T lymphocytes.
运输条件	Blue Ice
存放说明	4℃
参考文献	B Cell Chemotaxis, Migration, and Adhesion CC Chemokines and Receptors Chemokine Receptors Chemokines and Receptors in Allergy and Asthma Chemokines and Receptors in Angiogenesis Dendritic Cell Adhesion and Migration gamma delta T Cells Human CD Marker Products LTi Cells Monocyte Markers Natural Killer T (NKT) Cells Regulatory T Cells (Tregs) T Cell Migration/Adhesion Th17 Cells Th22 Cells

参考图片

Detection of CCR6 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD19 APC‑conjugated Monoclonal Antibody (Catalog # FAB4867A) and either (A) Mouse Anti-Human CCR6 Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB195F) or (B) Mouse IgG_2B Fluorescein Isotype Control (Catalog # IC0041F). View our protocol for Staining Membrane-associated Proteins.