Human CXCR2/IL-8 RB Fluorescein MAb (Clone 48311) (25 TESTS)【科瑞奥博】

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Human CXCR2/IL-8 RB Fluorescein MAb (Clone 48311) (25 TESTS)

货号： FAB331F-025 基本售价： 1407.8 元规格： 25 Tests

产品信息

概述
货号	FAB331F-025
简介	Clone 48311 was used by HLDA to establish CD designation
别名	beta; CD182 antigen; CD182; CDw128b; chemokine (C-X-C motif) receptor 2; chemokine (CXC) receptor 2; C-X-C chemokine receptor type 2; CXCR2 gene for IL8 receptor type B; CXC-R2; CXCR-2; GRO/MGSA receptor; High affinity interleukin-8 receptor B; IL-8 receptor type 2; IL-8R B; IL8R2; IL8RA; IL8RB; interleukin 8 receptor B; interleukin 8 receptor type 2; interleukin-8 receptor type B
全称	Interleukin 8 Receptor B
反应种属	Human
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects human CXCR2/IL-8 RB transfected NS0 cells but not the parental cell line. It does not cross-react with CXCR1 (IL-8 RA).
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	3579 (Human); 12765 (Mouse); 29385 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Enrichment of Foxp3+ CD4 regulatory T cells in migrated T cells to IL-6- and IL-8-expressing tumors through predominant induction of CXCR1 by IL-6. Authors: Eikawa S, Ohue Y, Kitaoka K J. Immunol., 2010;185(11):6734-40. Species: Human Sample Type: Whole Cells Application: Flow CXCR2 promotes ovarian cancer growth through dysregulated cell cycle, diminished apoptosis, and enhanced angiogenesis. Authors: Yang G, Rosen DG, Liu G Clin. Cancer Res., 2010;16(15):3875-86. Species: Human Sample Type: Whole Cells Application: ICC HIF-1 and NF-kappaB-mediated upregulation of CXCR1 and CXCR2 expression promotes cell survival in hypoxic prostate cancer cells. Authors: Maxwell PJ, Gallagher R, Seaton A, Wilson C, Scullin P, Pettigrew J, Stratford IJ, Williams KJ, Johnston PG, Waugh DJ Oncogene, 2007;26(52):7333-45. Species: Human Sample Type: Whole Cells Application: Flow Human CXCR2 (hCXCR2) takes over functionalities of its murine homolog in hCXCR2 knockin mice. Authors: Mihara K, Smit MJ, Krajnc-Franken M, Gossen J, Rooseboom M, Dokter W Eur. J. Immunol., 2005;35(9):2573-82. Species: Mouse Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from ascites
免疫原	NS0 mouse myeloma cell line transfected with human CXCR2/IL-8 RB Met1-Leu355 Accession # AAB25880
生物活性	Human
标记	Fluorescein
背景	CXCR2, also known as IL-8 RB, is a G protein-coupled chemokine receptor expressed on neutrophils. It binds IL-8, GRO alpha, GRO beta, GRO gamma, NAP-2, and ENA-78.
运输条件	Blue Ice
存放说明	4℃
参考文献	Chemokine Receptors Chemokines and Receptors in Angiogenesis Human CD Marker Products Macrophage Activation Markers Megakaryocytes Neuroinflammation Neutrophils T Cell Migration/Adhesion

参考图片

Detection of CXCR2/IL-8 RB in Human Peripheral Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human CXCR2/IL-8 RB Fluorescein-conjugated Monoclonal Antibody
(Catalog # FAB331F, filled histogram) or isotype control antibody (Catalog # IC003F, open histogram). View our protocol for Staining Membrane-associated Proteins.