货号 | FAB330N-025 |
简介 | Clone 42705 was used by HLDA to establish CD designation |
别名 | CD128; CD181 antigen; CD181; CDw128aC-C; chemokine (C-X-C motif) receptor 1; CKR-1; CMKAR1; C-X-C chemokine receptor type 1; CXC-R1; CXCR-1; High affinity interleukin-8 receptor A; IL-8 receptor type 1; IL-8R A; IL8R1; IL8RA; IL8RAC-C-CKR-1; IL8RBA; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A | 全称 | Interleukin 8 Receptor A |
反应种属 | Human |
应用 | Flow Cytometry(5 µL/106cells) |
目标/特异性 | Detects human CXCR1/IL-8 RA transfectants but not the parental cell line. It does not cross-react with human CXCR2. |
使用方法 | Flow Cytometry: 5 µL/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 3577 (Human); 227288 (Mouse); 54258 (Rat) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | NS0 mouse myeloma cell line transfected with human CXCR1/IL-8 RA Met1-Leu350 Accession # AAA59159 |
生物活性 | Human |
标记 | Alexa Fluor 700 |
背景 | The human C-X-C chemokine IL-8 is a potent neutrophil chemotactic and activating factor. Two distinct G protein-linked cell surface receptors, known as IL-8 RA (type I or CXCR1) and IL-8 RB (type II or CXCR2), can interact with the IL-8 molecule. These two receptors share 77% amino acid homology. CXCR1 expression has been documented on neutrophils, monocytes, and a small population of T cells. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Detection of CXCR1/IL‑8 RA in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human CXCR1/IL‑8 RA Alexa Fluor® 700-conjugated Monoclonal Antibody (Catalog # FAB330N, filled histogram) or isotype control antibody(Catalog # IC003N, open histogram). View our protocol for Staining Membrane-associated Proteins. |