Human LILRB4/CD85k/ILT3 Phycoerythrin MAb (Clone 293623) (25 TESTS)【科瑞奥博】

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Human LILRB4/CD85k/ILT3 Phycoerythrin MAb (Clone 293623) (25 TESTS)

货号： FAB24251P-025 基本售价： 1407.8 元规格： 25 Tests

产品信息

概述
货号	FAB24251P-025
别名	CD85 antigen-like family member K; CD85k antigen; CD85k; HM18; ILT3; ILT-3; ILT3CD85K; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains); LIR5; LIR5LILRB5; LIR-5subfamily B, member 4; member 4
全称	Leukocyte Immunoglobulin-like Receptor, Subfamily B (with TM and ITIM Domains), Member 4
反应种属	Human
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects human ILT3/CD85k in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with with recombinant human (rh) ILT5 is observed. No cross-reactivity with rhILT1, rhILT2, rhILT4, rhILT7, rhILT11, rhLIR-6 or rhLIR-8 is observed.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	11006 (Human); 14728 (Mouse)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Immune suppression and resistance mediated by constitutive activation of Wnt/beta-catenin signaling in human melanoma cells. J. Immunol., 2012;189(5):2110-7. Species: Human Sample Type: Whole Cells Application: Flow Identification of a New Phenotype of Tolerogenic Human Dendritic Cells Induced by Fungal Proteases from Aspergillus oryzae. Authors: Zimmer A, Luce S, Gaignier F, Nony E, Naveau M, Biola-Vidamment A, Pallardy M, Van Overtvelt L, Mascarell L, Moingeon P J. Immunol., 2011;186(7):3966-76. Species: Human Sample Type: Whole Cells Application: Flow Phenotypic and functional markers for 1alpha,25-dihydroxyvitamin D(3)-modified regulatory dendritic cells. Authors: Pedersen AW, Holmstrom K, Jensen SS, Fuchs D, Rasmussen S, Kvistborg P, Claesson MH, Zocca MB Clin. Exp. Immunol., 2010;157(1):48-59. Species: Human Sample Type: Whole Cells Application: Flow Maturation of dendritic cells depends on proteolytic cleavage by cathepsin X. Authors: Obermajer N, Svajger U, Bogyo M, Jeras M, Kos J J. Leukoc. Biol., 2008;84(5):1306-15. Species: Human Sample Type: Whole Cells Application: Flow Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals. Authors: Moir S, Ho J, Malaspina A, Wang W, DiPoto AC, OShea MA, Roby G, Kottilil S, Arthos J, Proschan MA, Chun TW, Fauci AS J. Exp. Med., 2008;205(8):1797-805. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Mouse myeloma cell line NS0-derived recombinant human ILT3/CD85k Pro17-His257 Accession # ABM86208
生物活性	Human
标记	Phycoerythrin
背景	Immunoglobulin-Like Transcript 3 (ILT3), also known as Leukocyte Immunoglobulin-Like Receptor subfamily B member 4 (LILRB4) and Leukocyte Immunoglobulin-like Receptor 5 (LIR-5), is a type I membrane protein that functions as a receptor for class I MHC antigens. It contains cytoplasmic ITIM motifs and is involved in the down-regulation of immune responses.
运输条件	Blue Ice
存放说明	4℃
参考文献	Angiopoietins, Angiopoietin-like Proteins, and Receptors B Cell Activation Common Macrophage Markers Co-stimulatory and Co-inhibitory Molecules Dendritic Cell ITIM/ITAM Immunoreceptors Dendritic Cell Pathogen Recognition/Uptake Human CD Marker Products ITIM/ITAM Immunoreceptors and Related Molecules Monocyte Markers T Cell Antigen Recognition

参考图片

Detection of LILRB4/CD85k/ILT3 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human IL‑3 R alpha /CD123 APC‑conjugated Monoclonal Antibody (Catalog # FAB301A) and either (A) Mouse Anti-Human LILRB4/CD85k/ILT3 PE‑conjugated Monoclonal Antibody (Catalog # FAB24251P) or (B) Mouse IgG_2A Phycoerythrin Isotype Control (Catalog # IC003P). View our protocol for Staining Membrane-associated Proteins.