Human Fc gamma RIIIA/B Allophycocyanin MAb (Clone 245536) (25 TESTS)【科瑞奥博】

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Human Fc gamma RIIIA/B Allophycocyanin MAb (Clone 245536) (25 TESTS)

货号： FAB2546A-025 基本售价： 1407.8 元规格： 25 Tests

产品信息

概述
货号	FAB2546A-025
别名	Fc gamma RIII (CD16); FcgRIII
全称	Fc gamma Receptor III
反应种属	Human
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects human Fc gamma RIIIA/B (CD16) in direct ELISAs. In direct ELISAs, approximately 10% cross-reactivity with recombinant human Fc gamma RIIA and recombinant mouse Fc gamma RIII is observed.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	14131 (Mouse); 102140945 (Cynomolgus Monkey)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. Authors: Hartl D, Krauss-Etschmann S, Koller B, Hordijk PL, Kuijpers TW, Hoffmann F, Hector A, Eber E, Marcos V, Bittmann I, Eickelberg O, Griese M, Roos D J. Immunol., 2008;181(11):8053-67. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Mouse myeloma cell line NS0-derived recombinant human Fc gamma RIIIA/B (CD16) Thr20-Gln208 Accession # O75015
生物活性	Human
标记	Allophycocyanin
背景	Fc gamma RIIIA and B are low affinity receptors for polyvalentimmune-complexed IgG. Fc gamma RIIIA is a transmembrane activating receptorexpressed by NK cells, T cells, monocytes, and macrophages. Fc gamma RIIIBis a non-activating GPI-linked decoy receptor expressed on neutrophilsand eosinophils.
运输条件	Blue Ice
存放说明	4℃
参考文献	Common Macrophage Markers Dendritic Cell ITIM/ITAM Immunoreceptors Dendritic Cell Pathogen Recognition/Uptake Fc Receptors gamma delta T Cells Group 1 ILCs Inflammatory/Monocyte-derived Dendritic Cells Isolation, Culture, and Identification of Natural Killer Cells ITIM/ITAM Immunoreceptors and Related Molecules Leukocyte Receptors/Markers in Allergy and Asthma Lymphoid Lineage Markers Macrophage Activation Markers Monocyte Markers Myeloid Lineage Markers Myeloid-derived Suppressor Cells (MDSC) Natural Killer T (NKT) Cells Neutrophils

参考图片

Detection of Fc gamma RIII (CD16) in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human Fc gamma RIII (CD16) APC‑conjugated Monoclonal Antibody (Catalog # FAB2546A) and Mouse Anti-Human CD14 PE‑conjugated Monoclonal Antibody (Catalog # FAB3832P). Quadrant markers were set based on control antibody staining (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins.