Human KIR2DS4/CD158i Allophycocyanin MAb (Clone 179315) (25 TESTS)【科瑞奥博】

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Human KIR2DS4/CD158i Allophycocyanin MAb (Clone 179315) (25 TESTS)

货号： FAB1847A-025 基本售价： 1407.8 元规格： 25 Tests

产品信息

概述
货号	FAB1847A-025
别名	CD158 antigen-like family member I; CD158i antigen; CD158i; cl-39; killer cell immunoglobulin-like receptor 2DS4; killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail4,nkat8; killer inhibitory receptor 4-1-2; KIR antigen 2DS4; KKA3KIR1D; MGC120019; MGC125315; MGC125317; MHC class I NK cell receptor; natural killer cell inhibitory receptor; Natural killer-associated transcript 8; NKAT-8; NKAT8KIR412; P58 natural killer cell receptor clones CL-39/CL-17; p58 NK receptor CL-39/CL-17
全称	Killer Cell Immunoglobulin-like Receptor, Two Domains, Short Cytoplasmic Tail, 4
反应种属	Human
应用	Flow Cytometry
目标/特异性	Detects KIR2DS4/CD158i in Western blots. In flow cytometry, this antibody stains cells transfected with KIR2DS4/CD158i. Does not stain cells transfected with KIR2DL1, 2DL2, 2DL3, 2DL4, 2DL5, 2DS1, 2DS2, 3DL1, 3DL2, or 3DS1.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	3809 (Human)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. 2DL1, 2DL2 and 2DL3 all contribute to KIR phenotype variability on human NK cells. Authors: Dunphy S, Guinan K, Chorcora C, Jayaraman J, Traherne J, Trowsdale J, Pende D, Middleton D, Gardiner C Genes Immun, 2015;16(5):301-10. Species: Human Sample Type: Whole Cells Application: Flow CMV drives clonal expansion of NKG2C+ NK cells expressing self-specific KIRs in chronic hepatitis patients. Authors: Beziat V, Dalgard O, Asselah T, Halfon P, Bedossa P, Boudifa A, Hervier B, Theodorou I, Martinot M, Debre P, Bjorkstrom NK, Malmberg KJ, Marcellin P, Vieillard V Eur. J. Immunol., 2012;42(2):447-57. Species: Human Sample Type: Whole Cells Application: Flow NK cell terminal differentiation: correlated stepwise decrease of NKG2A and acquisition of KIRs. Authors: Beziat V, Descours B, Parizot C, Debre P, Vieillard V PLoS ONE, 2010;5(8):e11966. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	BaF3 mouse pro-B cell line transfected with human KIR2DS4 Accession # P43632
生物活性	Human
标记	Allophycocyanin
背景	KIR2DS4 is an activating immunoglobulin-like receptor expressed on NK cells and some T cells. It has been implicated in the recognition of some HLA-C alleles (1). A deletion variant encoding a single domain secreted isoform of KIR2DS4 has also been described (2).
运输条件	Blue Ice
存放说明	4℃
参考文献	Katz, G. et al. (2001) J. Immunol. 166:7260. Maxwell, L. et al. (2002) Tissue Antigens 60:254.

参考图片

Detection of KIR2DS4/CD158i in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human KIR2DS4/CD158i APC‑conjugated Monoclonal Antibody (Catalog # FAB1847A) and Mouse Anti-Human NCAM‑1/CD56 PE‑conjugated Monoclonal Antibody (Catalog # FAB2408P). Quadrant markers were set based on control antibody staining (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins.