货号 | FAB197N-025 |
简介 | Clone 150503 was used by HLDA to establish CD designation |
别名 | BLR2C-C chemokine receptor type 7; C-C CKR-7; CC-CKR-7; CCR7; CCR-7; CD197 antigen; CD197; CDw197CC chemokine receptor 7; chemokine (C-C motif) receptor 7; CMKBR7chemokine (C-C) receptor 7; EBI1EBV-induced G protein-coupled receptor 1; EBV-induced G-protein coupled receptor 1; Epstein-Barr virus induced gene 1; Epstein-Barr virus induced G-protein coupled receptor; Epstein-Barr virus-induced G-protein coupled receptor 1; EVI1; lymphocyte-specific G protein-coupled peptide receptor; MIP-3 beta receptor |
反应种属 | Human |
应用 | Flow Cytometry |
目标/特异性 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
使用方法 | Flow Cytometry: 5 µL/106cells |
来源 | Monoclonal Mouse IgG2A Clone # 150503 |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 1236 (Human); 12775 (Mouse); 287673 (Rat) |
应用文献 | |
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Hypercytotoxicity and rapid loss of NKp44+ innate lymphoid cells during acute SIV infection. | |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | Human CCR7 transfectants Met1-Pro378 Accession # AAA58615 |
生物活性 | Human |
标记 | Alexa Fluor 700 |
背景 | CCR7 is a 7 transmembrane G protein coupled chemokine receptor. CCR7 is expressed on T cells and mature dendritic cells and transduces chemotactic signals in response to CCL19 and CCL21. Human CCR7 shares 87% amino acid sequence identity with mouse CCR7. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Detection of CCR7 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD4 PE‑conjugated Monoclonal Antibody (Catalog # FAB3791P) and either (A) Mouse Anti-Human CCR7 Alexa Fluor® 700‑conjugated Monoclonal Antibody (Catalog # FAB197N) or (B) Mouse IgG2A Alexa Fluor 700 Isotype Control (Catalog # IC003N). View our protocol for Staining Membrane-associated Proteins. | |
Detection of CCR7 in HEK293 Human Cell Line Transfected with Human CCR7 and eGFP by Flow Cytometry. The specificity of Mouse Anti-Human CCR7 Clone 150503 was demonstrated by its ability to react with (A) HEK293 human embryonic kidney cell line transfected with human CCR7 and not react with (B) irrelevant HEK293 transfectants. Antibody binding was monitored using Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0102B). |