Human KIR2DL1/KIR2DS5 Fluorescein MAb (Clone 143211) (25 TESTS)【科瑞奥博】

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Human KIR2DL1/KIR2DS5 Fluorescein MAb (Clone 143211) (25 TESTS)

货号： FAB1844F-025 基本售价： 1407.8 元规格： 25 Tests

产品信息

概述
货号	FAB1844F-025
别名	CD158a
反应种属	Human
应用	Flow Cytometry
目标/特异性	Detects human KIR2DL1/KIR2DS5 on transfected cells. It does not stain cells transfected with KIR2DL2, 2DL3, 2DL4, 2DL5, 2DS1, 2DS2, 2DS4, 3DL1, 3DL2, or 3DS1.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. New insights on the natural killer cell repertoire from a thorough analysis of cord blood cells Authors: P Rettman, C Willem, G David, R Riou, N Legrand, J Esbelin, A Cesbron, D Senitzer, K Gagne, C Retière J Leukoc Biol, 2016;0(0):. Species: Human Sample Type: Whole Cells Application: Flow 2DL1, 2DL2 and 2DL3 all contribute to KIR phenotype variability on human NK cells. Authors: Dunphy S, Guinan K, Chorcora C, Jayaraman J, Traherne J, Trowsdale J, Pende D, Middleton D, Gardiner C Genes Immun, 2015;16(5):301-10. Species: Human Sample Type: Whole Cells Application: Flow Uptake of CCR7 by KIR2DS4(+) NK cells is induced upon recognition of certain HLA-C alleles. Authors: Pesce S, Carlomagno S, Moretta A, Sivori S, Marcenaro E J Immunol Res, 2015;2015(0):754373. Species: Human Sample Type: Whole Cells Application: Flow The Human NK Cell Response to Yellow Fever Virus 17D Is Primarily Governed by NK Cell Differentiation Independently of NK Cell Education. Authors: Marquardt N, Ivarsson M, Blom K, Gonzalez V, Braun M, Falconer K, Gustafsson R, Fogdell-Hahn A, Sandberg J, Michaelsson J J Immunol, 2015;195(7):3262-72. Species: Human Sample Type: Whole Cells Application: Flow Tissue-Specific Education of Decidual NK Cells. Authors: Sharkey A, Xiong S, Kennedy P, Gardner L, Farrell L, Chazara O, Ivarsson M, Hiby S, Colucci F, Moffett A J Immunol, 2015;195(7):3026-32. Species: Human Sample Type: Whole Cells Application: Flow Expansion of CMV-mediated NKG2C+ NK cells associates with the development of specific de novo malignancies in liver-transplanted patients. Authors: Achour, Abla, Baychelier, Florence, Besson, Caroline, Arnoux, Armelle, Marty, Michel, Hannoun, Laurent, Samuel, Didier, Debre, Patrice, Vieillard, Vincent J Immunol, 2014;192(1):503-11. Species: Human Sample Type: Whole Cells Application: Flow Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection. Authors: Charoudeh H, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M Eur J Immunol, 2013;43(2):480-7. Species: Human Sample Type: whole cells Application: Flow Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus. Authors: Bjorkstrom NK, Lindgren T, Stoltz M, Fauriat C, Braun M, Evander M, Michaelsson J, Malmberg KJ, Klingstrom J, Ahlm C, Ljunggren HG J. Exp. Med., 2011;208(1):13-21. Species: Human Sample Type: Whole Cells Application: Flow Human Immunodeficiency Virus Type 1 Infection Is Associated with Increased NK Cell Polyfunctionality and Higher Levels of KIR3DL1+ NK Cells in Ugandans Carrying the HLA-B Bw4 Motif. Authors: Eller MA, Koehler RN, Kijak GH J. Virol., 2011;85(10):4802-11. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	BaF3 mouse pro-B cell line transfected with human KIR2DL1/KIR2DS5 Accession # P43626
生物活性	Human
标记	Fluorescein
背景	KIR2DL1 is one of several immunoglobulin-like receptors expressed on NK cells that bind MHC class I molecules and transmit inhibitory signals. KIR2DL1 is specific for HLA-C alleles with Asn77 and Lys80.
运输条件	Blue Ice
存放说明	4℃
参考文献	ITIM/ITAM Immunoreceptors and Related Molecules Killer Immunoglobulin-like Receptors (KIRs) Natural Killer T (NKT) Cells

参考图片

Detection of KIR2DL1/KIR2DS5 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human KIR2DL1/KIR2DS5 Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB1844F) and Mouse Anti-Human NCAM‑1/CD56 PE‑conjugated Monoclonal Antibody (Catalog # FAB2408P). Quadrant markers were set based on isotype control antibody staining (Catalog # IC002F). View our protocol for Staining Membrane-associated Proteins.