Human KIR2DL1/KIR2DS5 Allophycocyanin MAb (Clone 143211) (25 TESTS)【科瑞奥博】

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Human KIR2DL1/KIR2DS5 Allophycocyanin MAb (Clone 143211) (25 TESTS)

货号： FAB1844A-025 基本售价： 1407.8 元规格： 25 Tests

产品信息

概述
货号	FAB1844A-025
别名	CD158a
反应种属	Human
应用	Flow Cytometry
目标/特异性	Detects human KIR2DL1/KIR2DS5 on transfected cells. It does not stain cells transfected with KIR2DL2, 2DL3, 2DL4, 2DL5, 2DS1, 2DS2, 2DS4, 3DL1, 3DL2, or 3DS1.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. NK Cell Responses to Human Tick-Borne Encephalitis Virus Infection J Immunol, 2016;0(0):. Species: Human Sample Type: Whole Cells Application: Flow Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells. Authors: Marquardt N, Beziat V, Nystrom S, Hengst J, Ivarsson M, Kekalainen E, Johansson H, Mjosberg J, Westgren M, Lankisch T, Wedemeyer H, Ellis E, Ljunggren H, Michaelsson J, Bjorkstrom N J Immunol, 2015;194(6):2467-71. Species: Human Sample Type: Whole Cells Application: Flow Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection. Authors: Charoudeh H, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M Eur J Immunol, 2013;43(2):480-7. Species: Human Sample Type: whole cells Application: Flow CMV drives clonal expansion of NKG2C+ NK cells expressing self-specific KIRs in chronic hepatitis patients. Authors: Beziat V, Dalgard O, Asselah T, Halfon P, Bedossa P, Boudifa A, Hervier B, Theodorou I, Martinot M, Debre P, Bjorkstrom NK, Malmberg KJ, Marcellin P, Vieillard V Eur. J. Immunol., 2012;42(2):447-57. Species: Human Sample Type: Whole Cells Application: Flow NK cell terminal differentiation: correlated stepwise decrease of NKG2A and acquisition of KIRs. Authors: Beziat V, Descours B, Parizot C, Debre P, Vieillard V PLoS ONE, 2010;5(8):e11966. Species: Human Sample Type: Whole Cells Application: Flow Autologous antitumor activity by NK cells expanded from myeloma patients using GMP-compliant components. Authors: Alici E, Sutlu T, Bjorkstrand B, Gilljam M, Stellan B, Nahi H, Quezada HC, Gahrton G, Ljunggren HG, Dilber MS Blood, 2008;111(6):3155-62. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	BaF3 mouse pro-B cell line transfected with human KIR2DL1/KIR2DS5 Accession # P43626
生物活性	Human
标记	Allophycocyanin
背景	KIR2DL1 is one of several immunoglobulin-like receptors expressed on NK cells that bind MHC class I molecules and transmit inhibitory signals. KIR2DL1 is specific for HLA-C alleles with Asn77 and Lys80.
运输条件	Blue Ice
存放说明	4℃
参考文献	ITIM/ITAM Immunoreceptors and Related Molecules Killer Immunoglobulin-like Receptors (KIRs) Natural Killer T (NKT) Cells

参考图片

Detection of KIR2DL1/KIR2DS5 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human KIR2DL1/KIR2DS5 APC‑conjugated Monoclonal Antibody (Catalog # FAB1844A) and Mouse Anti-Human NCAM‑1/CD56 PE‑conjugated Monoclonal Antibody (Catalog # FAB2408P). Quadrant markers were set based on control antibody staining (Catalog # IC002A). View our protocol for Staining Membrane-associated Proteins.