Human CD11b/Integrin alpha M Phycoerythrin MAb (Cl 238446) (25 TESTS)【科瑞奥博】

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Human CD11b/Integrin alpha M Phycoerythrin MAb (Cl 238446) (25 TESTS)

货号： FAB16991P-025 基本售价： 1407.8 元规格： 25 Tests

产品信息

概述
货号	FAB16991P-025
别名	antigen CD11b (p170); CD11 antigen-like family member B; CD11b antigen; CD11b; CD11Bintegrin, alpha M (complement component receptor 3, alpha; also known as CD11b(p170), macrophage antigen alpha polypeptide); Cell surface glycoprotein MAC-1 subunit alpha; CR-3 alpha chain; CR3AMGC117044; Integrin alpha M; integrin alpha-M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; MAC-1; MAC1A; macrophage antigen alpha polypeptide; MO1A; neutrophil adherence receptor alpha-M subunit; Neutrophil adherence receptor; SLEB6
反应种属	Human
应用	Flow Cytometry
目标/特异性	Detects human Integrin alpha M/CD11b in direct ELISAs.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	3684 (Human); 16409 (Mouse)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. C-reactive protein (CRP) induces chemokine secretion via CD11b/ICAM-1 interaction in human adherent monocytes. Authors: Montecucco F, Steffens S, Burger F, Pelli G, Monaco C, Mach F J. Leukoc. Biol., 2008;84(4):1109-19. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Mouse myeloma cell line NS0-derived recombinant human Integrin alpha M/CD11b Phe17-Asn1105 Accession # NP_001139280
生物活性	Human
标记	Phycoerythrin
背景	The Integrin family proteins are heterodimeric transmembrane receptors composed of an alpha and a beta subunit. The Integrin alpha M subunit, also known as MAC-1 alpha subunit or CD11b, combines with the Integrin beta 2 subunit (CD18) to form the non-covalent heterodimer Integrin alpha M/ beta 2, also known as MAC-1 and Complement Receptor type 3 (CR3). Integrin alpha M/ beta 2 is expressed on granulocytes, macrophages, dendritic cells and natural killer cells. Upon activation, alpha M/ beta 2 can bind several ligands (including ICAM-1, Fibrinogen and the C3 Complement Fragment C3bi) to mediate phagocyte adhesion, migration and ingestion of complement-opsonized particles.
运输条件	Blue Ice
存放说明	4℃
参考文献	Acute Lymphoblastic Leukemia Acute Myeloid Leukemia Adhesion Molecules Adhesive Interactions in Allergy and Asthma B Cell Chemotaxis, Migration, and Adhesion B Cell Markers Basophils Common Macrophage Markers Conventional/Classical Dendritic Cells Granulocyte Markers HGF/SF Activation of Integrins Human CD Marker Products ICC / IHC Images: CD11b/Integrin alpha M Inflammatory/Monocyte-derived Dendritic Cells Integrin Ligands at a Glance (J. Cell. Sci.) Integrin Subunit Interactions Integrins and Associated Molecules Isolation, Culture, and Identification of Natural Killer Cells Langerhans and Dermal Dendritic Cells Monocyte Markers Mouse Tissue-Resident Macrophage Markers Myeloid Lineage Markers Myeloid-derived Suppressor Cells (MDSC) Neuroinflammation Neutrophils Plasmacytoid Dendritic Cells T Cell Migration/Adhesion

参考图片

Detection of Integrin alpha M/CD11b in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human Integrin alpha M/CD11b PE‑conjugated Monoclonal Antibody (Catalog # FAB16991P, filled histogram) or isotype control antibody (Catalog # IC0041P, open histogram). View our protocol for Staining Membrane-associated Proteins.