Human CXCR4 Fluorescein MAb (Clone 12G5) (25 TESTS)【科瑞奥博】

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Human CXCR4 Fluorescein MAb (Clone 12G5) (25 TESTS)

货号： FAB170F-025 基本售价： 1407.8 元规格： 25 Tests

产品信息

概述
货号	FAB170F-025
别名	CD184; chemokine (C-X-C motif) receptor 4; chemokine (C-X-C motif), receptor 4 (fusin); C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; D2S201ESDF-1 receptor; FB22; Fusin; HM89NPYRL; HSY3RR; LAP3; LCR1; LESTRCD184 antigen; Leukocyte-derived seven transmembrane domain receptor; leukocyte-derived seven-transmembrane-domain receptor; lipopolysaccharide-associated protein 3; neuropeptide Y receptor Y3; NPY3RWHIM; NPYR; NPYY3R; seven transmembrane helix receptor; seven-transmembrane-segment receptor, spleen; Stromal cell-derived factor 1 receptor
反应种属	Human
应用	Flow Cytometry
目标/特异性	Detects human CXCR4.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	7852 (Human); 12767 (Mouse); 60628 (Rat); 483900 (Canine); 493676 (Feline)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. The role of SDF-1-CXCR4/CXCR7 axis in biological behaviors of adipose tissue-derived mesenchymal stem cells in vitro. Authors: Li Q, Zhang A, Tao C, Li X, Jin P Biochem Biophys Res Commun, 2013;441(3):675-80. Species: Human Sample Type: whole cells Application: Flow Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo. Authors: Bosco MC, Pierobon D, Blengio F, Raggi F, Vanni C, Gattorno M, Eva A, Novelli F, Cappello P, Giovarelli M, Varesio L Blood, 2011;117(9):2625-39. Species: Human Sample Type: Whole Cells Application: Flow Identification of human NK17/NK1 cells. Authors: Pandya AD, Al-Jaderi Z, Hoglund RA, Holmoy T, Harbo HF, Norgauer J, Maghazachi AA PLoS ONE, 2011;6(10):e26780. Species: Human Sample Type: Whole Cells Application: Flow Pathogen induction of CXCR4/TLR2 cross-talk impairs host defense function. Authors: Hajishengallis G, Wang M, Liang S, Triantafilou M, Triantafilou K Proc. Natl. Acad. Sci. U.S.A., 2008;105(36):13532-7. Species: Human Sample Type: Whole Cells Application: Flow Chemokine receptor expression on allergen-specific T cells in asthma and allergic bronchopulmonary aspergillosis. Authors: Garcia G, Humbert M, Capel F, Rimaniol AC, Escourrou P, Emilie D, Godot V Allergy, 2007;62(2):170-7. Species: Human Sample Type: Whole Cells Application: Flow Aberration of CCR7 CD8 memory T cells from patients with systemic lupus erythematosus: an inducer of T helper type 2 bias of CD4 T cells. Authors: Sen Y, Chunsong H, Baojun H, Linjie Z, Qun L, San J, Qiuping Z, Junyan L, Zhang X, Jinquan T Immunology, 2004;112(2):274-89. Species: Human Sample Type: Whole Cells Application: Flow Histidyl-tRNA synthetase and asparaginyl-tRNA synthetase, autoantigens in myositis, activate chemokine receptors on T lymphocytes and immature dendritic cells. Authors: Howard OM, Dong HF, Yang D, Raben N, Nagaraju K, Rosen A, Casciola-Rosen L, Hartlein M, Kron M, Yiadom K, Dwivedi S, Plotz PH, Oppenheim JJ J. Exp. Med., 2002;196(6):781-91. Species: Human Sample Type: Whole Cells Application: Flow Expression and functional activity of CXCR-4 and CCR-5 chemokine receptors in human thymocytes. Authors: Zamarchi R, Allavena P, Borsetti A, Stievano L, Tosello V, Marcato N, Esposito G, Roni V, Paganin C, Bianchi G, Titti F, Verani P, Gerosa G, Amadori A Clin. Exp. Immunol., 2002;127(2):321-30. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from ascites
免疫原	CP-MAC-infected SUP-T1 human T cell lymphoblastic lymphoma line Accession # P61073
生物活性	Human
标记	Fluorescein
背景	CXCR4 is a G-protein-linked seven transmembrane spanning receptor that binds stromal cell-derived factor-1 (SDF-1). CXCR4 acts as a co-factor for T-cell tropic HIV-1 and -2 viral entry into cells.
运输条件	Blue Ice
存放说明	4℃
参考文献	Endres, M.J.et al. (1996) Cell 87:745.

参考图片

Detection of CXCR4 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR4 Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB170F) and Mouse Anti-Human CD19 PE‑conjugated Monoclonal Antibody (Catalog # FAB4867P). View our protocol for Staining Membrane-associated Proteins.