Anti-GITR Pure, human - Funct Grade
货号：
130-093-052 基本售价：
询价 规格：
EA
产品信息
概述| 货号 | 130-093-052 |
| 描述 | Clone DT5D3 recognizes human GITR (glucocorticoid-induced TNF receptor family-regulated gene), a type I transmembrane protein also known as AITR or TNFRSF18. GITR is expressed at low levels on resting T lymphocytes, expression is upregulated upon activation. Interaction of GITR with its ligand (GITRL) has been demonstrated to augment T cell activation, proliferation, and cytokine production. GITR signaling has been shown to regulate TCR-mediated apoptosis. GITR plays an important role in the function of CD4+CD25+Tregs. |
| 别名 | TNFRSF18, AITR, CD357, GITR-D |
| 克隆号 | DT5D3 |
| 同种亚型 | mouse IgG1 |
