Anti-FCeRIa pure, funct grade, human
货号:
130-096-004 基本售价:
询价 规格:
EA
产品信息
概述货号 | 130-096-004 |
描述 | Clone CRA1 detects the alpha subunit of the human high-affinity Fc receptor for IgE. The receptor is composed of one alpha, one beta and two disulfid-linked gamma subunits, of which the alpha subunit binds IgE1. FcεRIα is expressed on mast and basophilic cells and is up-regulated in the presence of IgE2,3. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. Antibody clone CRA1 does not inhibit binding of IgE4. It induces mast cell activation, followed by histamin release5. |
别名 | FCER1A, Fce1a, FcERI |
克隆号 | CRA1 |
同种亚型 | mouse IgG2b |