Hu TWEAK (CD255) PE CARL-2 100Tst
货号：
552890 基本售价：
16380.0 元 规格：
100Tst
产品信息
概述| 货号 | 552890 |
| 描述 | The CARL-2 monoclonal antibody specifically binds to TWEAK (TNF-related WEAK inducer of apoptosis), a type II transmembrane protein of approximately 1.4 kDa. TWEAK is also known as CD255. It is present as a cell surface bound or a secreted form, expressed on most tissues and non-lymphoid tumor cell lines, but weak or no expression on hematopoietic lineage lines. TWEAK is not detectable on resting PBMC, but its expression on peripheral blood monocytes is upregulated upon IFN-g stimulation. Reports indicate that TWEAK interacts with its receptor APO-3 and this interaction can lead to apoptosis, IL-8 secretion, NF-kB activation and endothelial cell proliferation. Clone CARL-1, a different monoclonal antibody, also reacts with CD255 (TWEAK) but to a different epitope. |
| 别名 | CD255; TWEAK; TNFSF12; APO3 ligand; APO3L; DR3LG |
| 同种亚型 | IgM |
| 反应种属 | Human (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human TWEAK Transfected Cell Line |
| 标记 | PE |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
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| 存储溶液 | Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide. |
