Hu TRAIL-R2 (CD262) PE YM366 100Tst
货号：
565499 基本售价：
10760.0 元 规格：
100Tst
产品信息
概述| 货号 | 565499 |
| 描述 | The YM366 monoclonal antibody specifically binds to TNF-related apoptosis-inducing ligand receptor 2 (TRAIL Receptor 2, TRAIL-R2) which is also known as, CD262, Death receptor 5 (DR5), TRICK2, or KILLER. CD262 is a type I transmembrane protein that is encoded by TNFRSF10B (Tumor necrosis factor receptor superfamily, member 10b). CD262 forms a homotrimeric receptor complex that can bind homotrimeric TRAIL (CD253/APO-2 Ligand) and transduce apoptotic signals intracellularly through its cytoplasmic death domain (DD). CD262 is differentially expressed on cells from a wide variety of normal tissues and tumors. CD262 expression is upregulated by I nterferon-α(IFN-α). |
| 别名 | TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9 |
| 同种亚型 | Mouse BALB/c IgG1, κ |
| 反应种属 | Human (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human DR5/TRAIL-R2 Recombinant Protein |
| 标记 | PE |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
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| 存储溶液 | Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide. |
