HU CD51 ALEXA 647 NKI-M9 25UG
货号：
565835 基本售价：
9845.0 元 规格：
25ug
产品信息
概述| 货号 | 565835 |
| 描述 | The NKI-M9 monoclonal antibody specifically binds to CD51, which is also known as Integrin alpha-V (ITGAV, α v), or Vitronectin receptor subunit alpha (VNRA, VTNR). CD51 is a type I transmembrane glycoprotein that is cleaved into 125 kDa and 25 kDa subunits which are disulfide linked. CD51 can form heterodimers with integrin β1 (CD29), β3 (CD61), β5, β6, or β8. CD51 is expressed on platelets, osteoclasts, endothelial cells, fibroblasts, macrophages, and some B cells, as well as neuroblastoma, melanoma, and hepatoma cells. Many extracellular matrix proteins with RGD-motifs can serve as ligands for CD51. In association with various integrin β chains, CD51 binds vitronectin, von Willebrand factor, fibronectin, thromb ospondin, osteopontin, fibrinogen, and laminin. The CD51 adhesion molecule plays important roles in leukocyte activation and localization, bone absorption, and angiogenesis. |
| 别名 | Integrin alpha-V; alphaV; αv; ITGAV; MSK8; VNRA; VTNR |
| 同种亚型 | Mouse BALB/c IgG2a, κ |
| 反应种属 | Human (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human Melanoma Cells |
| 标记 | Alexa 647 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated to Alexa Fluor® 647 under optimum conditions, and unreacted Alexa Fluor® 647 was removed.
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| 存储溶液 | Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
